Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically
manifests in midlife with motor, cognitive, and/or psychiatric symptoms. The disease is …

Huntington's disease (HD) is a devastating monogenic neurodegenerative disease
characterized by early, selective pathology in the basal ganglia despite the ubiquitous …

Neural circuits, such as synaptic plasticity and neural activity, are critical components of
healthy brain function. The consequent dynamic remodeling of neural circuits is an ongoing …

Oligodendrocyte loss in neurological disease leaves axons vulnerable to damage and
degeneration, and activity-dependent myelination may represent an endogenous …

Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the degeneration of
both upper and lower motor neurons. Despite decades of research, we still to date lack a …

The understanding of the functional and structural changes occurring in the cerebral cortex
and basal ganglia in Huntington's disease (HD) has benefited considerably from the …

Huntington's disease is an autosomal, dominantly inherited neurodegenerative disease
caused by an expansion of the CAG repeats in exon 1 of the huntingtin gene. Neuronal …

Alzheimer's disease (AD) is associated with aberrant neuronal activity, which is believed to
critically determine disease symptoms. How these activity alterations emerge, how stable …

Huntington's disease (HD) is a neurodegenerative disease that results in motor and
cognitive dysfunction, leading to early death. HD is caused by an expansion of CAG repeats …

Sleep disruption is a common invisible symptom of neurological dysfunction in Huntington's
disease (HD) that takes an insidious toll on well-being of patients. Here we used …