The Na/K-ATPase (NKA), or Na pump, is a member of the P-type ATPase superfamily. In
addition to pumping ions across cell membrane, it is engaged in assembly of multiple …

The Na+-K+-ATPase (NKA) differs from most other ion transporters, not only in its capacity to
maintain a steep electrochemical gradient across the plasma membrane, but also as a …

St John's wort (SJW), an extract of the medicinal plant Hypericum perforatum, is widely used
as a herbal antidepressant. Recently, this agent has been found to adversely affect the …

In this brief review we discuss some aspects of the Na+ pump and its roles in mediating the
effects of ouabain and endogenous ouabain (EO): i) in regulating the cytosolic Ca 2+ …

Na, K-ATPase is a protein ubiquitously expressed in the plasma membrane of all animal
cells and vitally essential for their functions. A specialized functional diversity of the Na, K …

Marked loss of skeletal muscle mass occurs under various conditions of disuse, but the
molecular and cellular mechanisms leading to atrophy are not completely understood. We …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), identified for the first time
in Wuhan, China, causes coronavirus disease 2019 (COVID-19), which moved from …

There is a great need for treatment that arrests progression of chronic kidney disease.
Increased albumin in urine leads to apoptosis and fibrosis of podocytes and tubular cells …

The Na/K-ATPase α1 polypeptide supports both ion-pumping and signaling functions. The
Na/K-ATPase α3 polypeptide differs from α1 in both its primary structure and its tissue …

Abstract The Na/K‐ATPase as an essential ion pump was discovered more than 50 years
ago (Skou (1989) Biochim. Biophys. Acta 1000, 439–446; Feraille and Doucet (2001) …