CB2 receptor in microglia: the guardian of self-control

JA Komorowska-Müller, AC Schmöle - International journal of molecular …, 2020 - mdpi.com
Microglia are key to maintaining the homeostasis of the brain. These immune cells of the
brain can be our biggest ally in fighting infections, but can worsen pathology or hinder …

Autophagic regulation of p62 is critical for cancer therapy

MA Islam, MA Sooro, P Zhang - International journal of molecular …, 2018 - mdpi.com
Sequestosome1 (p62/SQSTM 1) is a multidomain protein that interacts with the autophagy
machinery as a key adaptor of target cargo. It interacts with phagophores through the LC3 …

NF-κB signaling in ovarian cancer

BS Harrington, CM Annunziata - Cancers, 2019 - mdpi.com
The NF-κB signaling pathway is a master and commander in ovarian cancer (OC) that
promotes chemoresistance, cancer stem cell maintenance, metastasis and immune evasion …

The hallmarks of ovarian cancer stem cells and niches: Exploring their harmonious interplay in therapy resistance

T Motohara, GJ Yoshida, H Katabuchi - Seminars in Cancer Biology, 2021 - Elsevier
The concept of a “cancer stem cell” has evolved over the past decades, and research on
cancer stem cell biology has entered into a stage of remarkable progress. Cancer stem cells …

Cisplatin triggers cancer stem cell enrichment in platinum-resistant cells through NF-κB-TNFα-PIK3CA loop

B Thakur, P Ray - Journal of Experimental & Clinical Cancer Research, 2017 - Springer
Background Parallel to complex alteration in molecular and cellular events, enrichment of
cancer stem cells (CSC) contributes significantly in deliberation and maintenance of …

[HTML][HTML] Sanguinarine inhibits epithelial ovarian cancer development via regulating long non-coding RNA CASC2-EIF4A3 axis and/or inhibiting NF-κB signaling or …

S Zhang, T Leng, Q Zhang, Q Zhao, X Nie… - Biomedicine & …, 2018 - Elsevier
Objective This study aimed to investigate the antitumor effects and possible regulatory
mechanisms of sanguinarine in epithelial ovarian cancer. Material and methods The effects …

Photothermal therapy (PTT) is an effective treatment measure against solid tumors which fails to respond conventional chemo/radiation therapies in clinic

SK Mishra, AC Dhadve, A Mal, BPK Reddy, A Hole… - Biomaterials …, 2022 - Elsevier
Photothermal therapy (PTT) has emerged as a fast, precisive, and cost-effective anticancer
therapy protocol. Here we applied our previously designed nanomaterial (Tocophotoxil) for …

Saccharomyces cerevisiae inhibits growth and metastasis and stimulates apoptosis in HT-29 colorectal cancer cell line

R Sambrani, J Abdolalizadeh, L Kohan… - Comparative Clinical …, 2019 - Springer
Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide.
Accumulating evidence has suggested that probiotics affect cellular pathways and specific …

Triple Reporter Assay: A Non-Overlapping Luciferase Assay for the Measurement of Complex Macromolecular Regulation in Cancer Cells Using a New Mushroom …

A Mujawar, P Phadte, KA Palkina, NM Markina… - Sensors, 2023 - mdpi.com
This study demonstrates the development of a humanized luciferase imaging reporter based
on a recently discovered mushroom luciferase (Luz) from Neonothopanus nambi. In vitro …

Long term treatment of metformin impedes development of chemoresistance by regulating cancer stem cell differentiation through taurine generation in ovarian cancer …

A Bishnu, A Sakpal, N Ghosh, P Choudhury… - … International Journal of …, 2019 - Elsevier
Abstract Development of resistance poses a significant challenge to effective first-line
platinum based therapy for epithelial ovarian cancer patients. Cancer Stem Cells are …