Thrombotic thrombocytopenic purpura: pathophysiology, diagnosis, and management

S Sukumar, B Lämmle, SR Cataland - Journal of clinical medicine, 2021 - mdpi.com
Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy
characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and …

Syndromes of thrombotic microangiopathy

JN George, CM Nester - New England Journal of Medicine, 2014 - Mass Medical Soc
Syndromes of Thrombotic Microangiopathy | New England Journal of Medicine Skip to main
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Caplacizumab treatment for acquired thrombotic thrombocytopenic purpura

M Scully, SR Cataland, F Peyvandi… - … England Journal of …, 2019 - Mass Medical Soc
Background In acquired thrombotic thrombocytopenic purpura (TTP), an immune-mediated
deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained …

Caplacizumab for acquired thrombotic thrombocytopenic purpura

F Peyvandi, M Scully, JA Kremer Hovinga… - … England Journal of …, 2016 - Mass Medical Soc
Background Acquired thrombotic thrombocytopenic purpura (TTP) is caused by aggregation
of platelets on ultralarge von Willebrand factor multimers. This microvascular thrombosis …

Thrombotic thrombocytopenic purpura

JA Kremer Hovinga, P Coppo, B Lämmle… - Nature reviews Disease …, 2017 - nature.com
Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is
characterized by the concomitant occurrence of often severe thrombocytopenia …

Thrombotic thrombocytopenic purpura

BS Joly, P Coppo, A Veyradier - Blood, The Journal of the …, 2017 - ashpublications.org
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic
microangiopathy characterized by microangiopathic hemolytic anemia, severe …

Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross …

E Mariotte, E Azoulay, L Galicier, E Rondeau… - The Lancet …, 2016 - thelancet.com
Background Thrombotic thrombocytopenic purpura is a thrombotic microangiopathy related
to a severe deficiency of ADAMTS13 (a disintegrin and metalloprotease with …

Thrombotic thrombocytopenic purpura: diagnostic criteria, clinical features, and long-term outcomes from 1995 through 2015

EE Page, JA Kremer Hovinga, DR Terrell… - Blood …, 2017 - ashpublications.org
Our objective was to describe new observations from the Oklahoma Thrombotic
Thrombocytopenic Purpura (TTP) Registry experience (November 1995 through December …

[HTML][HTML] The international hereditary thrombotic thrombocytopenic purpura registry: key findings at enrollment until 2017

HA van Dorland, MM Taleghani, K Sakai… - …, 2019 - ncbi.nlm.nih.gov
Congenital thrombotic thrombocytopenic purpura is an autosomal recessive inherited
disease with a clinically heterogeneous course and an incompletely understood genotype …

Preemptive rituximab prevents long-term relapses in immune-mediated thrombotic thrombocytopenic purpura

M Jestin, Y Benhamou, AS Schelpe… - Blood, The Journal …, 2018 - ashpublications.org
Preemptive rituximab infusions prevent relapses in immune thrombotic thrombocytopenic
purpura (iTTP) by maintaining normal ADAMTS13 activity. However, the long-term outcome …