The centrosome cycle: centriole biogenesis, duplication and inherent asymmetries

EA Nigg, T Stearns - Nature cell biology, 2011 - nature.com
Centrosomes are microtubule-organizing centres of animal cells. They influence the
morphology of the microtubule cytoskeleton, function as the base for the primary cilium and …

The centrosome in cells and organisms

M Bornens - Science, 2012 - science.org
The centrosome acts as the main microtubule-nucleating organelle in animal cells and plays
a critical role in mitotic spindle orientation and in genome stability. Yet, despite its central …

Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity

AC O'Neill, F Uzbas, G Antognolli, F Merino… - Science, 2022 - science.org
The centrosome provides an intracellular anchor for the cytoskeleton, regulating cell
division, cell migration, and cilia formation. We used spatial proteomics to elucidate protein …

[图书][B] Cell movements: from molecules to motility

D Bray - 2000 - taylorfrancis.com
Cell Movements vividly describes how complex movements can arise from the properties
and behaviors of biological molecules. This second edition is updated throughout with …

[HTML][HTML] Centrioles, centrosomes, and cilia in health and disease

EA Nigg, JW Raff - Cell, 2009 - cell.com
Centrioles are barrel-shaped structures that are essential for the formation of centrosomes,
cilia, and flagella. Here we review recent advances in our understanding of the function and …

The centrosome is an actin-organizing centre

F Farina, J Gaillard, C Guérin, Y Couté… - Nature cell …, 2016 - nature.com
Microtubules and actin filaments are the two main cytoskeleton networks supporting
intracellular architecture and cell polarity. The centrosome nucleates and anchors …

The extracellular matrix guides the orientation of the cell division axis

M Théry, V Racine, A Pépin, M Piel, Y Chen… - Nature cell …, 2005 - nature.com
The cell division axis determines the future positions of daughter cells and is therefore
critical for cell fate. The positioning of the division axis has been mostly studied in systems …

3D-structured illumination microscopy provides novel insight into architecture of human centrosomes

KF Sonnen, L Schermelleh, H Leonhardt… - Biology …, 2012 - journals.biologists.com
Centrioles are essential for the formation of cilia and flagella. They also form the core of the
centrosome, which organizes microtubule arrays important for cell shape, polarity, motility …

Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole

M Ohta, T Ashikawa, Y Nozaki, H Kozuka-Hata… - Nature …, 2014 - nature.com
Formation of one procentriole next to each pre-existing centriole is essential for centrosome
duplication, robust bipolar spindle assembly and maintenance of genome integrity …

Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer

RA Neumüller, JA Knoblich - Genes & development, 2009 - genesdev.cshlp.org
Cell division is commonly thought to involve the equal distribution of cellular components
into the two daughter cells. During many cell divisions, however, proteins, membrane …