Being the largest internal organ of the human body with the unique ability of self-
regeneration, the liver is involved in a wide variety of vital functions that require highly …

Mesenchymal stem cells (MSCs) are known as promising sources for cancer therapy and
can be utilized as vehicles in cancer gene therapy. MSC-derived exosomes are central …

Hepatocellular carcinoma (HCC) accounts for over 80% of liver cancer cases and is highly
malignant, recurrent, drug‐resistant, and often diagnosed in the advanced stage. It is clear …

Abstract Background MicroRNA-122 (miR-122), a pivotal liver-specific miRNA, is frequently
repressed in hepatocellular carcinoma (HCC) and associated with poor prognosis. Long …

Both acute and chronic liver toxicity represents a major global health burden and an
important cause of morbidity and lethality worldwide. Despite epochal progress in the …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide. HCC patients are commonly diagnosed at an advanced stage, for which highly …

MicroRNAs (miRNAs) can act as oncogenes or tumor suppressors, capable of up or down‐
regulating gene expression during tumorigenesis; they are diagnostic biomarkers or …

Hepatocellular carcinoma (HCC) is the second most lethal cancer and a leading cause of
cancer-related mortality worldwide. Immune checkpoint inhibitors (ICIs) significantly …

Hepatitis C virus (HCV) replication requires annealing of a liver specific microRNA, miR-122
to 2 sites on 5′ untranslated region (UTR). While, microRNAs downregulate gene …

Background and Aim Patients with primary sclerosing cholangitis (PSC) are at high risk for
the development of cholangiocarcinoma (CC). Analysis of micro ribonucleic acid (MiRNA) …