Challenges of neuropathic pain: focus on diabetic neuropathy

DC Rosenberger, V Blechschmidt… - Journal of Neural …, 2020 - Springer
Neuropathic pain is a frequent condition caused by a lesion or disease of the central or
peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain …

[HTML][HTML] Diabetic neuropathy

EL Feldman, BC Callaghan, R Pop-Busui… - Nature reviews Disease …, 2019 - nature.com
The global epidemic of prediabetes and diabetes has led to a corresponding epidemic of
complications of these disorders. The most prevalent complication is neuropathy, of which …

Painful and painless diabetic neuropathies: what is the difference?

P Shillo, G Sloan, M Greig, L Hunt, D Selvarajah… - Current diabetes …, 2019 - Springer
Abstract Purpose of Review The prevalence of diabetes mellitus and its chronic
complications are increasing to epidemic proportions. This will unfortunately result in …

Characteristics of the intestinal flora in patients with peripheral neuropathy associated with type 2 diabetes

Y Wang, X Ye, D Ding, Y Lu - Journal of International …, 2020 - journals.sagepub.com
Objective To study the characteristics of the intestinal flora in patients with diabetic
peripheral neuropathy (DPN) and analyze the association between the intestinal flora and …

[HTML][HTML] Diabetic neuropathy: Past, present, and future

J Quiroz-Aldave, M Durand-Vásquez… - Caspian journal of …, 2023 - ncbi.nlm.nih.gov
Background: A sedentary lifestyle and an unhealthy diet have considerably increased the
incidence of diabetes mellitus worldwide in recent decades, which has generated a high …

Neurons and microglia; a sickly-sweet duo in diabetic pain neuropathy

T Rajchgot, SC Thomas, JC Wang, M Ahmadi… - Frontiers in …, 2019 - frontiersin.org
Diabetes is a common condition characterized by persistent hyperglycemia. High blood
sugar primarily affects cells that have a limited capacity to regulate their glucose intake …

Diabetic peripheral neuropathy in people with type 2 diabetes: too little too late

S Javed, T Hayat, L Menon, U Alam… - Diabetic …, 2020 - Wiley Online Library
Diabetic peripheral neuropathy in people with type 2 diabetes is poorly managed because
of its insidious onset, delayed diagnosis and more complex aetiology resulting from the …

Preclinical study of diabetic foot ulcers: From pathogenesis to vivo/vitro models and clinical therapeutic transformation

Y Du, J Wang, W Fan, R Huang… - International Wound …, 2023 - Wiley Online Library
Diabetic foot ulcer (DFU), a common intractable chronic complication of diabetes mellitus
(DM), has a prevalence of up to 25%, with more than 17% of the affected patients at risk of …

Formononetin ameliorates diabetic neuropathy by increasing expression of SIRT1 and NGF

MJ Oza, YA Kulkarni - Chemistry & biodiversity, 2020 - Wiley Online Library
Diabetic neuropathy is commonly observed complication in more than 50% of type 2
diabetic patients. Histone deacetylases including SIRT1 have significant role to protect …

[HTML][HTML] Investigating the Interplay between Mitophagy and Diabetic Neuropathy: Uncovering the hidden secrets of the disease pathology

K Hushmandi, B Einollahi, R Aow, SB Suhairi… - Pharmacological …, 2024 - Elsevier
Mitophagy, the cellular process of selectively eliminating damaged mitochondria, plays a
crucial role in maintaining metabolic balance and preventing insulin resistance, both key …