Programmed cell death (PCD) or apoptosis is a mechanism which is crucial for all
multicellular organisms to control cell proliferation and maintain tissue homeostasis as well …

Chemistry, traditionally being the science of synthesis and structural manipulations of
molecules, has gradually undertaken the more challenging task of biology-oriented …

Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and
pathological conditions. It is also one of the most studied topics among cell biologists. An …

Apoptosis is an evolutionarily conserved sequential process of cell death to maintain a
homeostatic balance between cell formation and cell death. It is a vital process for normal …

Inhibitor of apoptosis (IAP) family comprises a group of endogenous proteins that function as
main regulators of caspase activity and cell death. They are considered the main culprits in …

The ability to synthesise small peptidomimetics that mimic the secondary structure of
proteins is an ever expanding area of research directed at sourcing new medicinal agents …

Natural peptides are an important class of chemical mediators, essential for most vital
processes. What limits the potential of the use of peptides as drugs is their low bioavailability …

Apoptosis, an important form of programmed cell death (PCD), is a tightly regulated cellular
process to eliminate unwanted or damaged cells. Resistance of apoptosis is a hallmark of …

First described by the groups of Sharpless (Rostovtsev et al., Angew. Chem., Int. Ed., 2002,
41, 2596) and Meldal (Tornøe et al., J. Org. Chem., 2002, 67, 3057) in 2002, Cu (I)-catalyzed …

Peptidomimetics play a fundamental role in drug design due to their preferential properties
regarding natural peptides. In particular, compounds possessing nitrogen-containing …