Wilms' tumor 1 gene in hematopoietic malignancies: Clinical implications and future directions

P Luo, W Jing, K Yi, S Wu, F Zhou - Leukemia & Lymphoma, 2020 - Taylor & Francis
Abstract The Wilms' tumor 1 (WT1) gene is an important regulatory molecule that plays a
vital role in cell growth and development. Initially, knowledge of WT1 was mostly limited to …

Overexpression of EPS8 is associated with poor prognosis in patients with acute lymphoblastic leukemia

Y He, Z Liang, M Wu, Q Wen, L Deng, C Song, B Wu… - Leukemia research, 2015 - Elsevier
Molecular markers have become an invaluable tool in monitoring disease status particularly
of leukemias, as bone marrow samples can be easily collected for analysis during all stages …

WT1 overexpression affecting clinical outcome in non-hodgkin lymphomas and adult acute lymphoblastic leukemia

Z Ujj, G Buglyó, M Udvardy, G Vargha, S Biró… - Pathology & Oncology …, 2014 - Springer
Abstract The Wilms tumor 1 (WT1) gene has a complex role as a transcriptional regulator,
acting as tumor suppressor or oncogene in different malignancies. The prognostic role of its …

Молекулярный мониторинг течения острых миелоидных лейкозов по уровню экспрессии гена WT1 после аллогенной трансплантации гемопоэтических …

НН Мамаев, АВ Горбунова, ИМ Бархатов… - Клиническая …, 2015 - cyberleninka.ru
Цель. Оценить возможности серийного определения уровня экспрессии гена WT1 для
предсказания и диагностики посттрансплантационных рецидивов острых миелоидных …

A rare case of pediatric T-cell acute lymphoblastic leukemia with myeloid mimicry

W Ni, J Liu, K Deng, Z Zeng, Q Kong, X Weng - Discover Oncology, 2024 - Springer
Acute lymphoblastic leukemia (ALL) with granular blasts was historically referred to as
“granular ALL”, but this is not recognized as a distinct entity in the current WHO …

WT1 overexpression predicted good outcomes in adult B-cell acute lymphoblastic leukemia patients receiving chemotherapy

S Wang, C Wang, T Li, W Wang, Q Hao, X Xie… - …, 2020 - Taylor & Francis
Objectives: The prognostic role of WT1 in acute lymphoblastic leukemia (ALL) is still
controversial. No study has focused on the prognostic role of WT1 expression in adult B-ALL …

[HTML][HTML] Prognostic impact of WT-1 gene expression in Egyptian children with acute lymphoblastic leukemia

AA Hagag, IM Badraia, SM Hassan… - … Journal of Hematology …, 2016 - ncbi.nlm.nih.gov
Background Acute lymphoblastic leukemia (ALL) is the most common childhood cancer
representing 23% of pediatric cancers. Wilms' tumor-1 gene is a novel prognostic factor …

Wilms' tumor gene (WT1) expression levels as prognostic marker in pediatric acute lymphoblastic leukemia

NL Mikhael, AM Ibrahim, MA Helmy… - The Egyptian Journal of …, 2020 - journals.lww.com
Background Wilms' tumor gene (WT1) encodes a transcription factor that has a role in kidney
development and malignancy. WT1 is shown to be overexpressed in most adult acute …

[HTML][HTML] Efficacy of Chemotherapy in Acute Leukemia Patients Resistant to Previous Standard Treatment According to the Series Measurement of WT1 Gene …

N Mamaev, Y Gudozhnikova, T Gindina… - Clinical …, 2018 - old.bloodjournal.ru
Aim. To estimate the efficacy of chemotherapy in acute leukemia patients resistant to
previous standard treatment according to the series measurement of WT1 expression …

Эффективность химиотерапии у больных острыми лейкозами с резистентностью к предшествующему стандартному лечению по данным серийного …

НН Мамаев, ЯВ Гудожникова, ТЛ Гиндина… - Клиническая …, 2018 - cyberleninka.ru
Цель. Оценить эффективность химиотерапии при резистентности к стандартному
лечению у больных острыми лейкозами по данным серийного измерения уровня …