Advanced Oxidation Protein Products Induce G1/G0‐Phase Arrest in Ovarian Granulosa Cells via the ROS‐JNK/p38 MAPK‐p21 Pathway in Premature Ovarian …

XY Zhou, J Zhang, Y Li, YX Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
The mechanism underlying the role of oxidative stress and advanced oxidation protein
products (AOPPs) in the aetiology of premature ovarian insufficiency (POI) is poorly …

[PDF][PDF] Etanercept protects ovarian reserve against ischemia/reperfusion injury in a rat model

MK Eken, GS Ersoy, EI Kaygusuz… - Archives of Medical …, 2019 - termedia.pl
Results Tissue GSH and SOD levels were significantly higher, while MDA and MPO levels
were significantly lower in the I/R+ etanercept group than in the I/R group (p< 0.05, p< 0.01 …

Involvement of PTEN and FOXO3a proteins in the protective activity of protocatechuic acid against cisplatin-induced ovarian toxicity in mice

BB Gouveia, RS Barberino, RL dos Santos Silva… - Reproductive …, 2021 - Springer
The present study evaluated the effects of protocatechuic acid (PCA) after cisplatin-induced
ovarian toxicity in mice and if PTEN and FOXO3a proteins are involved in PCA action. The …

[HTML][HTML] Protective effect of minocycline on Bax and Bcl-2 gene expression, histological damages and oxidative stress induced by ovarian torsion in adult rats

MK Roshanaee, SH Abtahi-Eivary… - … Journal of Fertility & …, 2022 - ncbi.nlm.nih.gov
Background Minocycline is a widely used bacteriostatic antibiotic with various functions. The
aim of this study was to investigate impact of apoptotic genes in ovary of the …

Protective effects of nebivolol on ovarian ischemia–reperfusion injury in rat

S Colak, B Gurlek, A Topcu, L Tumkaya… - Journal of Obstetrics …, 2020 - Wiley Online Library
Aim Ovarian torsion is a common gynecological emergency of reproductive ages, occurring
at rates of 2.7–7.4%. This study aimed to evaluate the antioxidant effects of Nebivolol (NEB) …

The protective effects of glycyrrhetinic acid and chrysin against ischemia‐reperfusion injury in rat ovaries

R Melekoglu, O Ciftci, S Eraslan… - BioMed research …, 2018 - Wiley Online Library
Objective. To evaluate the protective effects of glycyrrhetinic acid (GA) and chrysin (CH) on
experimental ischemia‐reperfusion (I/R) injury in rat ovaries using tissue oxidative stress …

An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats

A Topcu, G Balik, M Atak, T Mercantepe… - European journal of …, 2019 - Elsevier
Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and
thus cause severe gynecological and hormonal deficiencies. The discovery of new agents is …

N-acetylcysteine administration improves the redox and functional gene expression levels in spleen, mesenteric lymph node and gastrocnemius muscle in piglets …

Y Zhang, J Tian, C Wang, T Wu, D Yi, L Wang, D Zhao… - Animals, 2023 - mdpi.com
Simple Summary Few studies reported the effects of NAC on the lungs, liver, spleen, lymph
nodes, and gastrocnemius muscles of PEDV-infected piglets. Therefore, it is very meaningful …

[HTML][HTML] Novel molecular mechanisms underlying the ameliorative effect of N-acetyl-L-cysteine against ϒ-radiation-induced premature ovarian failure in rats

EM Mantawy, RS Said, DH Kassem… - Ecotoxicology and …, 2020 - Elsevier
Radiotherapy represents a critical component in cancer treatment. However, premature
ovarian failure (POF) is a major hurdle of deleterious off-target effects in young females …

Magnesium: does it reduce ischemia/reperfusion injury in an adnexal torsion rat model?

E Celik Kavak, F Gulcu Bulmus, O Bulmus… - Drug design …, 2018 - Taylor & Francis
Aim The aim of the present study was to assess the protective effects of magnesium sulfate
(MgSO4) on ischemia/reperfusion (I/R) induced ovarian damage in a rat ovarian torsion …