The glycocalyx, a thick layer of carbohydrates, surrounds the cell wall of most bacterial and
parasitic pathogens. Recognition of these unique glycans by the human immune system …

Glycoconjugate vaccines based on bacterial capsular polysaccharides (CPS) have been
extremely successful in preventing bacterial infections. The glycan antigens for the …

Clostridioides difficile is a Gram-positive, spore-forming, toxin-producing anaerobe, and an
important nosocomial pathogen. Due to the strictly anaerobic nature of the vegetative form …

The surface of cells is coated with a dense layer of glycans, known as the cell glycocalyx.
The complex glycans in the glycocalyx are involved in various biological events, such as …

The worldwide emergence of epidemic strains of Clostridium difficile linked to increased
disease severity and mortality has resulted in greater research efforts toward determining …

Carbohydrate antigens have shown promise as important targets for developing effective
vaccines and pathogen detection strategies. Modifying purified microbial glycans through …

Clostridium difficile is a spore-forming gram-positive bacillus, and the leading cause of
antibiotic-associated nosocomial diarrhea and colitis in the industrialized world. With the …

Introduction Clostridium difficile is a significant cause of morbidity and mortality in hospitals,
nursing homes, and long-term care facilities. The bacteria can produce 3 toxins, of which the …

Clostridium difficile infection (CDI) is recognized as a major cause of nosocomial diseases
ranging from antibiotic related diarrhea to fulminant colitis. Emergence during the last 2 …

Constipation and diarrhea are common in autistic patients. Treatment with antibiotics against
bacteria appears to partially alleviate autistic-related symptoms. Clostridium bolteae is a …