[HTML][HTML] Protein kinase inhibitors as targeted therapy for glioblastoma: a meta-analysis of randomized controlled clinical trials
Glioblastoma (GBM) is the most common and lethal primary brain tumor. The standard
treatment for newly diagnosed GBM includes surgical resection, when feasible, followed by …
treatment for newly diagnosed GBM includes surgical resection, when feasible, followed by …
[HTML][HTML] Lck Function and Modulation: Immune Cytotoxic Response and Tumor Treatment More Than a Simple Event
JB De Sanctis, JV Garmendia, H Duchová, V Valentini… - Cancers, 2024 - mdpi.com
Simple Summary Lck is an important kinase that plays a key role in the physiological
responses of T lymphocytes as well as in several other tissues such as the lung, intestine …
responses of T lymphocytes as well as in several other tissues such as the lung, intestine …
[HTML][HTML] Gene Therapy for Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is a devastating, aggressive primary brain tumor with poor
patient outcomes and a five-year survival of less than 10%. Significant limitations to effective …
patient outcomes and a five-year survival of less than 10%. Significant limitations to effective …
[HTML][HTML] Novel antimicrobial and antitumor agents bearing pyridine-1, 2, 4-triazole-3-thione-hydrazone scaffold: synthesis, biological evaluation, and molecular …
A Šermukšnytė, M Stasevych… - …, 2024 - pmc.ncbi.nlm.nih.gov
A series of target 4-substituted-5-(2-(pyridine-2-ylamino) ethyl)-2, 4-dihydro-3H-1, 2, 4-
triazole-3-thiones and their chloro analogs 7–21 were synthesized in a reaction of the …
triazole-3-thiones and their chloro analogs 7–21 were synthesized in a reaction of the …
Glioma Stem Cells—Features for New Therapy Design
N Pećina-Šlaus, R Hrašćan - Cancers, 2024 - mdpi.com
Simple Summary Gliomas are deleterious central nervous system tumors that harbor cellular
heterogeneity and infiltrative capabilities. They are biologically aggressive and highly …
heterogeneity and infiltrative capabilities. They are biologically aggressive and highly …
[HTML][HTML] Mitochondrial Dysfunction: Effects and Therapeutic Implications in Cerebral Gliomas
G Caruso, R Laera, R Ferrarotto, CG Garcia Moreira… - Medicina, 2024 - mdpi.com
Gliomas are the most common primary brain tumors, representing approximately 28% of all
central nervous system tumors. These tumors are characterized by rapid progression and …
central nervous system tumors. These tumors are characterized by rapid progression and …
Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma
J Yan, X Xiao - Frontiers in Medicine, 2024 - frontiersin.org
Primary esophageal small cell carcinoma (PESC) is a rare, extremely aggressive
malignancy characterized by rapid growth, early metastasis, and poor prognosis. This study …
malignancy characterized by rapid growth, early metastasis, and poor prognosis. This study …