Objectives The holy grail of biomarker research in periodontology is to develop a high
impact diagnostics which have a significant impact on clinical decision-making, patient …

The pineal gland hormone melatonin continues to be of considerable interest to biomedical
researchers. Of particular interest is the pattern of secretion of melatonin in relation to sleep …

Background and Objectives: There is evidence that melatonin could improve the periodontal
status and also glycemic control of patients with diabetes mellitus. Therefore, the aim of this …

Background and Objectives The purpose of this article was to summarize what is known
about the function of melatonin in the oral cavity. Material and Methods Databases were …

The detection of salivary biomarkers has a potential application in early diagnosis and
monitoring of periodontal inflammation. However, searching sensitive salivary biomarkers …

Traditional clinical measurements such as probing pocket depth, bleeding on probing,
clinical attachment loss; plaque index and radiographs used for periodontal diagnosis are …

Background: Periodontitis is a chronic disease with a complex etiology that includes
bacterial colonization, excessive inflammation, and oxidative stress. The hormone melatonin …

Methods: An extensive review of the scientific literature was carried out using PubMed,
Science Direct, Google Scholar and the Cochrane base. Research articles were collected …

Saliva has the potential to be used as a diagnostic and monitoring tool for various diseases
if biomarkers of an adequate sensitivity and specificity could be identified. Several reviews …

Personalized Oral Healthcare has recently become the new trend word in medicine and
dentistry. In this context, saliva diagnostics using various biomarkers seem to be the …