Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …

Benzimidazole derivatives play important role in medical field with so many
Pharmacological activities such as antimicrobial, antiviral, antidiabetic and anticancer …

In this study 12 novel benzimidazole compounds bearing hydrazone moiety were
synthesized in order to investigate their possible antibacterial and antifungal activity …

To affiliate multiple bioactivities in a compact heteronuclei, two series of benzimidazole
based 1, 3, 4-oxadiazoles were synthesized and assessed in vitro for their efficacy as …

Tetrasubstituted 2-acetylthiophene derivative 5 was synthesized and then condensed with
various nitrogen nucleophiles such as 5-amino-1, 2, 4-triazole, 2-aminobenzimidazole …

Multi-target EGFR, VEGFR-2 and PDGFR inhibitors are highly useful anticancer agents with
improved therapeutic efficacies. In this work, we used two virtual screening methods, support …

The development of efficient and mild methods to assemble C–N bonds represents an
important and appealing goal in modern synthetic chemistry. Recently,(hetero) aryl C (sp2) …

A series of novel benzimidazole derivatives were synthesized and characterized by 1H
NMR, 13C NMR, MS, IR and HRMS spectra. All the new compounds were screened for their …

Various triheterocyclic compounds containing benzimidazole, thiophene, and 1, 2, 4-triazole
rings (3–6) were synthesized and screened for their antioxidant activities. The structures of …

Tetrahydrofuran is a privileged structural moiety in many important organic compounds. In
this work, we have developed a simple and mild catalytic oxidative amination of …