Vitamin D (VitD) is a prohormone most noted for the regulation of calcium and phosphate
levels in circulation, and thus of bone metabolism. Inflammatory and immune cells not only …

The incidence of allergic diseases is increasing, both in developed and developing
countries, concomitantly with the rise in living standards and the adoption of a'western …

Purpose Vitamin D is a potent immunomodulator capable of dampening inflammatory
signals in several cell types involved in the asthmatic response. Its deficiency has been …

Respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD) are major
complications to preterm birth. Hypovitaminosis D is prevalent in pregnancy. We …

Asthma is a chronic inflammatory disease of the airway with extensive airway remodeling.
The ethical issues associated with the studies in asthmatic patients, required development of …

Background Subepithelial fibrosis is a characteristic hallmark of airway remodeling in
asthma. A critical regulator of fibrosis, transforming growth factor β (TGF-β), can induce …

Respiratory viral infections are common respiratory diseases. Influenza viruses, RSV and
SARS-COV2 have the potential to cause severe respiratory infections. Numerous studies …

Vitamin D is well known for its role as a calcium regulator and in maintenance of phosphate
homeostasis in musculoskeletal health, and fibroblast growth factor 23 (FGF23) and its …

We have previously demonstrated increased airway smooth muscle (ASM) mass and airway
hyperresponsiveness in whole-life vitamin D–deficient female mice. In this study, we aimed …

Asthma is a chronic disease of the lung associated with airway hyperresponsiveness (AHR),
airway obstruction and airway remodeling. Airway remodeling involves differentiation of …