The role of natural killer cells in autoimmune diseases
Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …
lymphoid progenitors, were discovered in early 1970's. They are members of innate …
Human NK cells: surface receptors, inhibitory checkpoints, and translational applications
NK cells play important roles in innate defenses against viruses and in the control of tumor
growth and metastasis. The regulation/induction of NK cell function is mediated by an array …
growth and metastasis. The regulation/induction of NK cell function is mediated by an array …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …
immunology and flow cytometry community. They provide the theory and key practical …
Guidelines for the use of flow cytometry and cell sorting in immunological studies*
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …
Killer Ig-like receptors (KIRs): their role in NK cell modulation and developments leading to their clinical exploitation
Natural killer (NK) cells contribute to the first line of defense against viruses and to the
control of tumor growth and metastasis spread. The discovery of HLA class I specific …
control of tumor growth and metastasis spread. The discovery of HLA class I specific …
[HTML][HTML] NK cells and ILCs in tumor immunotherapy
Cells of the innate immunity play an important role in tumor immunotherapy. Thus, NK cells
can control tumor growth and metastatic spread. Thanks to their strong cytolytic activity …
can control tumor growth and metastatic spread. Thanks to their strong cytolytic activity …
Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization
Background Programmed death 1 (PD-1) is an immunologic checkpoint that limits immune
responses by delivering potent inhibitory signals to T cells on interaction with specific …
responses by delivering potent inhibitory signals to T cells on interaction with specific …
Innate or adaptive immunity? The example of natural killer cells
Natural killer (NK) cells were originally defined as effector lymphocytes of innate immunity
endowed with constitutive cytolytic functions. More recently, a more nuanced view of NK …
endowed with constitutive cytolytic functions. More recently, a more nuanced view of NK …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …
performing flow cytometry experiments and includes comprehensive sections describing …
Targeting natural killer cells and natural killer T cells in cancer
Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share
some phenotypical and functional similarities. Both cell types can rapidly respond to the …
some phenotypical and functional similarities. Both cell types can rapidly respond to the …