Platelets are essential effector cells in hemostasis. Aside from their role in coagulation,
platelets are now recognized as major inflammatory cells with key roles in the innate and …

Neutrophils are important components of the innate immune system that mediate pathogen
defense by multiple processes including phagocytosis, release of proteolytic enzymes …

Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …

Abstract Background In March 2008, the D: A: D study published results demonstrating an
increased risk of myocardial infarction (MI) for patients on abacavir (ABC). We describe …

Background: Evidence is conflicting about the association of abacavir use and
cardiovascular disease (CVD) among HIV-infected individuals. Previous studies may have …

Objective: Assessing whether the previously reported association between abacavir (ABC)
and cardiovascular disease (CVD) remained amongst contemporarily treated people with …

Background: Whilst reporting improved renal and bone safety profiles, studies have noted
changes in lipid profiles among people living with HIV (PLWH) receiving antiretroviral …

HIV-infected patients are at greater risk for both venous and arterial thrombosis. Chronic
immune activation and inflammation in these patients appears to contribute to coagulation …

Background Although associations between older antiretroviral drug classes and
cardiovascular disease in people living with HIV are well described, there is a paucity of …

Cardiovascular diseases and thrombotic events became major clinical problems in the
combined antiretroviral therapy (cART) era. Although the precise mechanisms behind these …