microRNAs biogenesis, functions and role in tumor angiogenesis

T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …

The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance–a focus on signaling pathways interplay

A Ismail, AI Abulsoud, D Fathi, A Elshafei… - … -Research and Practice, 2022 - Elsevier
One of the most prevalent and lethal forms of gynecological cancer is ovarian cancer (OC),
which is often diagnosed in its latter, deadly stages. The OC's high mortality and …

MicroRNA key to angiogenesis regulation: MiRNA biology and therapy

A Tiwari, B Mukherjee, M Dixit - Current cancer drug targets, 2018 - ingentaconnect.com
Angiogenesis is involved in maintaining normal physiological processes like embryonic
development, wound healing, inflammation and reproduction. Pathogenesis of various …

The role of early growth response 1 (EGR1) in brain plasticity and neuropsychiatric disorders

F Duclot, M Kabbaj - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
It is now clearly established that complex interactions between genes and environment are
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …

[HTML][HTML] Organic materials for rechargeable sodium-ion batteries

Y Xu, M Zhou, Y Lei - Materials Today, 2018 - Elsevier
Rechargeable sodium-ion batteries (SIBs) have attracted great attention for large-scale
electric energy storage applications and smart grid owing to the abundance of Na resources …

Targeting miRNAs and other non-coding RNAs as a therapeutic approach: an update

E Bayraktar, R Bayraktar, H Oztatlici… - Non-coding RNA, 2023 - mdpi.com
Since the discovery of the first microRNAs (miRNAs, miRs), the understanding of miRNA
biology has expanded substantially. miRNAs are involved and described as master …

Platelets reduce anoikis and promote metastasis by activating YAP1 signaling

M Haemmerle, ML Taylor, T Gutschner… - Nature …, 2017 - nature.com
Thrombocytosis is present in more than 30% of patients with solid malignancies and
correlates with worsened patient survival. Tumor cell interaction with various cellular …

New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications

Y Wang, L Wang, C Chen, X Chu - Molecular cancer, 2018 - Springer
Angiogenesis is essential for tumor growth and metastasis. Understanding the regulation of
tumor angiogenesis has become increasingly important. MicroRNAs (miRNAs) are small …

EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis

L Li, AH Ameri, S Wang, KH Jansson, OM Casey… - Oncogene, 2019 - nature.com
Abstract Early growth response-1 (EGR1) is a transcription factor correlated with prostate
cancer (PC) progression in a variety of contexts. For example, EGR1 levels increase in …

The role of HOX transcription factors in cancer predisposition and progression

B Li, Q Huang, GH Wei - Cancers, 2019 - mdpi.com
Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily
genes, play pivotal roles in many aspects of cellular physiology, embryonic development …