Protein aggregation in biotherapeutics can reduce their activity and effectiveness. It may
also promote immune reactions responsible for severe adverse effects. The impact of plastic …

Liquid–liquid phase separation (LLPS) constitutes a crucial phenomenon in biological self-
organization, not only intervening in the formation of membraneless organelles but also …

Crowding effects significantly influence the phase behavior and the structural and dynamic
properties of the concentrated protein mixtures present in the cytoplasm of cells or in the …

The diffusion of proteins is significantly affected by macromolecular crowding. Molecular
simulations accounting for protein interactions at atomic resolution are useful for …

The Brownian dynamics of a colloidal particle is consistently modified by the presence in the
solvent of other particles of comparable size, whose effects on the particle diffusion …

We construct a coarse-grained, structure-based, low-resolution, 6-bead flexible model of
bovine serum albumin (BSA, PDB: 4F5S), which is a popular example of a globular protein …

With continuously improving signal-to-noise ratios, a statistically sound analysis of quasi-
elastic neutron scattering (QENS) spectra requires to fit increasingly complex models which …

The diffusive properties of colloid suspension depend on several parameters such as
temperature [1], additives [2, 3] or crowding [4]. However, in biological environments, the …