Helicobacter pylori Outer Membrane Vesicle Size Determines Their Mechanisms of Host Cell Entry and Protein Content
L Turner, NJ Bitto, DL Steer, C Lo, K D'Costa… - Frontiers in …, 2018 - frontiersin.org
Gram-negative pathogens ubiquitously shed outer membrane vesicles (OMVs) that play a
central role in initiating and regulating pathogenesis in the host. Due to their highly …
central role in initiating and regulating pathogenesis in the host. Due to their highly …
Adjuvants to increase immunogenicity of SARS-CoV-2 RBD and support maternal–fetal transference of antibodies in mice
Adjuvants are important components of vaccines, increasing immunogenicity and
modulating the immune response. SARS-CoV-2 vaccines are still being developed in order …
modulating the immune response. SARS-CoV-2 vaccines are still being developed in order …
Evaluation of intranasal and subcutaneous route of immunization in neonatal mice using DODAB-BF as adjuvant with outer membrane vesicles of Neisseria …
FA de Oliveira Santos, N Lincopan, E De Gaspari - Immunobiology, 2018 - Elsevier
Abstract Background The Neisseria meningitidis bacterium is a Gram-negative diplococcus
that can be classified into different serogroups according to the capsular structure. Six of …
that can be classified into different serogroups according to the capsular structure. Six of …
Dioctadecyldimethylammonium bromide (DODAB-BF) as a new adjuvant for maternal-fetal immunization in mice against Neisseria meningitidis: evaluation of …
AF de Almeida, E De Gaspari - Pathogens and disease, 2018 - academic.oup.com
Neisseria meningitidis bacterium is a Gram-negative diplococcus. Among their serogroups,
the B is one of the main causes of invasive meningococcal disease. Newborns and children …
the B is one of the main causes of invasive meningococcal disease. Newborns and children …
Neisseria lactamica antigens complexed with a novel cationic adjuvant
EB Gaspar, AS Rosetti, N Lincopan… - Human vaccines & …, 2013 - Taylor & Francis
Colonization of the nasopharynx by non-pathogenic Neisseria species, including N.
lactamica, has been suggested to lead to the acquisition of natural immunity against …
lactamica, has been suggested to lead to the acquisition of natural immunity against …
Intranasal and Intramuscular Immunization with Outer Membrane Vesicles from Serogroup C Meningococci Induced Functional Antibodies and Immunologic Memory
A Izeli Portilho, V Araujo Correa… - Immunological …, 2022 - Taylor & Francis
Background Immunization is the key to prevent invasive meningococcal disease (IMD),
caused by Neisseria meningitidis. Outer membrane vesicles (OMVs) can be used as …
caused by Neisseria meningitidis. Outer membrane vesicles (OMVs) can be used as …
Individual variability in humoral response of immunized outbred mice and cross-reactivity with prevalent Brazilian Neisseria meningitidis strains
GT de Lima, E De Gaspari - Biologicals, 2018 - Elsevier
Discussion In this study we used an antigenic preparation composed by OMVs from
Neisseria meningitidis serogroup B and aluminum hydroxide as adjuvant. The OMVs …
Neisseria meningitidis serogroup B and aluminum hydroxide as adjuvant. The OMVs …
[PDF][PDF] Application of prime-boost as a novel vaccination strategy against microbial pathogens
D Gaspari - FORMATEX, 2011 - researchgate.net
The main public health strategy for reducing infection is vaccination. However, because
immune responses can differ, due to the age-related and genetic characteristics of the …
immune responses can differ, due to the age-related and genetic characteristics of the …
The Design of New Adjuvants for Mucosal Immunity to Neisseria meningitidis B in Nasally Primed Neonatal Mice for Adult Immune Response
T Ferreira, E De Gaspari - The Scientific World Journal, 2012 - Wiley Online Library
The aim of this study was to determine the value of detoxified Shiga toxins Stx1 and Stx2
(toxoids of Escherichia coli) as mucosal adjuvants in neonatal mice for immunogenicity …
(toxoids of Escherichia coli) as mucosal adjuvants in neonatal mice for immunogenicity …
[HTML][HTML] Immunogenicity of antigens from outer membrane vesicles of Neisseria meningitidis associated with bilayer fragment of dioctadecyldimethylammonium in …
FM Rinaldi, EB Gaspar, LT Brito… - Clinical and …, 2021 - ncbi.nlm.nih.gov
Purpose In the present study, meningococcal serogroup B outer membrane vesicles (OMVs)
were associated with bilayer fragments of a cationic lipid, dioctadecyldimethylammonium …
were associated with bilayer fragments of a cationic lipid, dioctadecyldimethylammonium …