Critical assessment of relevant methods in the field of biosensors with direct optical detection based on fibers and waveguides using plasmonic, resonance, and …

G Gauglitz - Analytical and Bioanalytical Chemistry, 2020 - Springer
Direct optical detection has proven to be a highly interesting tool in biomolecular interaction
analysis to be used in drug discovery, ligand/receptor interactions, environmental analysis …

Through the looking-glass-Recent developments in reflectometry open new possibilities for biosensor applications

P Fechner, G Gauglitz, G Proll - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Label-free biosensing has developed from niche application to state of the art biosensing
technique throughout the past decades. The reason for the raise of acceptance for this …

Analytical evaluation of sensor measurements

G Gauglitz - 2018 - Springer
Teaching about sensors requires references to analytical definitions, and a discussion of
sensor principles combined with detection principles, the process of sensor interaction with …

Anabel: an online tool for the real-time kinetic analysis of binding events

SD Krämer, J Wöhrle, C Rath… - … and biology insights, 2019 - journals.sagepub.com
Anabel (Ana lysis of b inding e vents+ l) is an open source online software tool (www.
skscience. org/anabel) for the convenient analysis of molecular binding interactions …

Determination of the invA gene of Salmonella using surface plasmon resonance along with streptavidin aptamer amplification

P Lei, H Tang, S Ding, X Ding, D Zhu, B Shen… - Microchimica Acta, 2015 - Springer
We have developed a sensitive method for the determination of Salmonella by integrating a
streptavidinylated aptamer (SA-aptamer) as a signal amplification unit along with a modified …

Development of a new parallelized, optical biosensor platform for label-free detection of autoimmunity-related antibodies

O Bleher, A Schindler, MX Yin, AB Holmes… - Analytical and …, 2014 - Springer
Autoimmune diseases are characterized by the presence of autoantibodies in serum of
affected patients. The heterogeneity of autoimmune relevant antigens creates a variety of …

Surface chemistry and morphology in single particle optical imaging

F Ekiz-Kanik, DD Sevenler, NL Ünlü, M Chiari… - …, 2017 - degruyter.com
Biological nanoparticles such as viruses and exosomes are important biomarkers for a
range of medical conditions, from infectious diseases to cancer. Biological sensors that …

Ultrasensitive label-free immunoassay for optical determination of amitriptyline and related tricyclic antidepressants in human serum

AK Krieg, G Gauglitz - Analytical chemistry, 2015 - ACS Publications
The present work focuses on the development of a label-free and ultrasensitive
immunoassay for the detection of the drug amitriptyline in human serum. Reflectometric …

Numerical techniques for high-throughput reflectance interference biosensing

D Sevenler, M Selim Ünlü - Journal of Modern Optics, 2016 - Taylor & Francis
We have developed a robust and rapid computational method for processing the raw
spectral data collected from thin film optical interference biosensors. We have applied this …

A multi-analyte biosensor for the simultaneous label-free detection of pathogens and biomarkers in point-of-need animal testing

M Ewald, P Fechner, G Gauglitz - Analytical and bioanalytical chemistry, 2015 - Springer
For the first time, a multi-analyte biosensor platform has been developed using the label-free
1-lambda-reflectometry technique. This platform is the first, which does not use imaging …