SUMMARY β-Lactam antibiotics have been widely used as therapeutic agents for the past
70 years, resulting in emergence of an abundance of β-lactam-inactivating β-lactamases …

Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary
directions for Klebsiella pneumoniae, which pose a great threat in clinical settings. Multiple …

There is an enormous global public health burden due to antimicrobial-resistant (AMR)
Klebsiella pneumoniae high-risk clones. K. pneumoniae ST307 and ST147 are recent …

Background We evaluated the distribution of carbapenem and colistin resistance
mechanisms of clinical E. coli and K. pneumoniae isolates from Iran. Methods 165 non …

Background. The global spread of carbapenemase-producing Enterobacterales has
become an epidemiological risk for healthcare systems by limiting available antimicrobial …

Klebsiella pneumoniae is a Gram-negative organism and a major public health threat. In this
study, we used whole-genome sequences to characterize 32 carbapenem-resistant K …

Carbapenemase-producing Klebsiella pneumoniae (CPKP) emerged in Greece in 2002 and
became endemic thereafter. Driven by a notable variability in the phenotypic testing results …

Abstract Introduction In Greece, the spread of carbapenem-resistant Enterobacteriaceae in
humans has led to the reintroduction of colistin as a therapeutic agent. Unfortunately, colistin …

For addressing the issue of antimicrobial drug resistance in developing countries, it is
important to investigate the characteristics of carbapenemase-producing organisms. We …

The increasing prevalence and dissemination of carbapenemase-producing
Enterobacterales represent a serious concern for public health. We studied the genetic …