Ageing is a process that gradually increases the organism's vulnerability to death. It affects
different biological pathways, and the underlying cellular mechanisms are complex. In view …

Aims/hypothesis Recent clinical studies indicate that glucagon-like peptide-1 (GLP-1)
analogues prevent acute cardiovascular events in type 2 diabetes mellitus but their …

Phytochemicals from fruit and vegetables reduce systemic inflammation. This study
examined the effects of an encapsulated fruit and vegetable (F&V) juice concentrate on …

Aims/hypothesis Non-alcoholic fatty liver disease (NAFLD) is frequently associated with type
2 diabetes mellitus. Progression of NAFLD is mediated, among other things, by activation of …

Ageing is a complex multifactorial process that results in many changes in physiological
changes processes that ultimately increase susceptibility to a wide range of diseases. As …

Associations between granins (secretogranin II (SgII) and chromogranin A and B (CgA and
CgB)) and gonadotrophins (LH and FSH) have been reported in rodents and they may …

Previous studies indicate a role of CDKN2A/2B/2BAS genes in atherosclerosis and type 2
diabetes mellitus (T2DM). Progression of these diseases is accompanied by T-cell …

Background Type 1 diabetes mellitus (T1DM) patients display increased risk of
cardiovascular disease (CVD) and are characterized by a diminished regulatory T (Treg) cell …

Aims Cellular senescence in type 2 diabetes mellitus (T2DM) has received widespread
attention. However, the cellular senescence molecules involved in T2DM are unclear …

Aims/hypothesis Although insulin resistance often leads to type 2 diabetes mellitus, its early
stages are often unrecognised, thus reducing the probability of successful prevention and …