Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

Transglutaminase 2 (TG2 or tissue transglutaminase) is a highly complex multifunctional
protein that acts as transglutaminase, GTPase/ATPase, protein disulfide isomerase, and …

Celiac disease is a chronic small bowel disorder caused by an abnormal immune response
to an array of epitopes of wheat gluten and related proteins of rye and barley in genetically …

Abstract Transglutaminase 2 (TG2) is a multifunctional protein that can function as a
transglutaminase, G protein, kinase, protein disulfide isomerase, and as an adaptor protein …

Transglutaminases form a large family of intracellular and extracellular enzymes that
catalyse the Ca2+‐dependent post‐translational modification of proteins. Despite significant …

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by hyperglycemia
due to progressive immune-mediated destruction of insulin-producing pancreatic islet β …

FXIII (Factor XIII) is a Ca2+-dependent enzyme which forms covalent ϵ-(γ-glutamyl) lysine
cross-links between the γ-carboxy-amine group of a glutamine residue and the ϵ-amino …

Over the last three decades, the scaffold proteins prohibitins-1 and-2 (PHB1/2) have
emerged as key signaling proteins regulating a myriad of signaling pathways in health and …

Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by pancreatic β cell
destruction induced by islet reactive T cells that have escaped central tolerance. Many …

Transglutaminase 2 (TG2) is the most widely distributed and most abundantly expressed
member of the transglutaminase family of enzymes, a group of intracellular and extracellular …