Mesoporous silica nanoparticles: importance of surface modifications and its role in drug delivery

SK Natarajan, S Selvaraj - RSC advances, 2014 - pubs.rsc.org
Mesoporous nanoparticles are special examples of silica nanoparticles. They are well
known for their variety of applications in various fields including biomedicine. This has been …

Comprehensive understanding of the synthesis and formation mechanism of dendritic mesoporous silica nanospheres

P Hao, B Peng, BQ Shan, TQ Yang, K Zhang - Nanoscale Advances, 2020 - pubs.rsc.org
The interest in the design and controlled fabrication of dendritic mesoporous silica
nanospheres (DMSNs) emanates from their widespread application in drug-delivery …

Antibiotic-loaded silica nanoparticle–collagen composite hydrogels with prolonged antimicrobial activity for wound infection prevention

GS Alvarez, C Hélary, AM Mebert, X Wang… - Journal of Materials …, 2014 - pubs.rsc.org
Silica–collagen type I nanocomposite hydrogels are evaluated as medicated dressings to
prevent infection in chronic wounds. Two antibiotics, gentamicin and rifamycin, are …

A redox-responsive drug delivery system based on RGD containing peptide-capped mesoporous silica nanoparticles

ZY Li, JJ Hu, Q Xu, S Chen, HZ Jia, YX Sun… - Journal of Materials …, 2015 - pubs.rsc.org
In this paper, an intracellular glutathione (GSH) responsive mesoporous silica nanoparticle
(MSN-SS-RGD) was developed as a drug nanocarrier by immobilizing the gatekeeper (RGD …

Mesoporous silica nanoparticles for 19 F magnetic resonance imaging, fluorescence imaging, and drug delivery

T Nakamura, F Sugihara, H Matsushita, Y Yoshioka… - Chemical …, 2015 - pubs.rsc.org
Multifunctional mesoporous silica nanoparticles (MSNs) are good candidates for multimodal
applications in drug delivery, bioimaging, and cell targeting. In particular, controlled release …

A reversible light-operated nanovalve on mesoporous silica nanoparticles

D Tarn, DP Ferris, JC Barnes, MW Ambrogio… - Nanoscale, 2014 - pubs.rsc.org
Two azobenzene α-cyclodextrin based nanovalves are designed, synthesized and
assembled on mesoporous silica nanoparticles. Under aqueous conditions, the cyclodextrin …

Multifunctional hybrid silica nanoparticles for controlled doxorubicin loading and release with thermal and pH dual response

X Hu, X Hao, Y Wu, J Zhang, X Zhang… - Journal of materials …, 2013 - pubs.rsc.org
Controlled drug loading and release into tumor cells to increase the intracellular drug
concentration is a major challenge for cancer therapy due to resistance and inefficient …

Chemical modification of inorganic nanostructures for targeted and controlled drug delivery in cancer treatment

L Zhang, Y Li, CY Jimmy - Journal of Materials Chemistry B, 2014 - pubs.rsc.org
Chemically modified inorganic nanoparticles (NPs) hold great promise for biomedical
applications. In this review, we examine the recent advances in nanotechnology for targeted …

A magnetic mesoporous silica nanoparticle-based drug delivery system for photosensitive cooperative treatment of cancer with a mesopore-capping agent and …

NŽ Knežević, VSY Lin - Nanoscale, 2013 - pubs.rsc.org
Lately, there has been a growing interest in anticancer therapy with a combination of
different drugs that work by different mechanisms of action, which decreases the possibility …

pH-and glutathione-responsive release of curcumin from mesoporous silica nanoparticles coated using tannic acid–Fe (iii) complex

S Kim, S Philippot, S Fontanay, RE Duval… - RSC …, 2015 - pubs.rsc.org
A novel pH-and glutathione-responsive drug delivery system has been developed by
deposition of tannic acid (TA)–Fe (III) complex on the surface of mesoporous silica …