Tumor vascularization occurs through several distinct biological processes, which not only
vary between tumor type and anatomic location, but also occur simultaneously within the …

Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) pathway is a
common signaling pathway used to transduce signals from the extracellular to the …

PURPOSE Sunitinib, a multitargeted tyrosine kinase inhibitor (TKI), is approved for
advanced gastrointestinal stromal tumor (GIST) after imatinib failure. Ripretinib is a switch …

Angiogenesis is the process of formation of new blood vessels from existing ones. Vessels
serve the purpose of providing oxygen, nutrients and removal of waste from the cells. The …

Myeloid-derived suppressor cells (MDSCs) contribute to the induction of an immune
suppressive/anergic, tumor permissive environment. MDSCs act as immunosuppression …

Formononetin, an isoflavone, is extracted from various medicinal plants and herbs, including
the red clover (Trifolium pratense) and Chinese medicinal plant Astragalus membranaceus …

Angiogenesis is a process of generation of de-novo blood vessels from already existing
vasculature. It has a crucial role in different physiological process including wound healing …

Vascular endothelial growth factors (VEGFs) are the key regulators of vasculogenesis in
normal and oncological development. VEGF-A is the most studied angiogenic factor …

Glioblastoma (GBM) is the most malignant primary brain tumor without effective therapies.
Since bevacizumab was FDA approved for targeting vascular endothelial growth factor …

Malignant pheochromocytoma–paraganglioma: pathogenesis, TNM... : Current Opinion in
Endocrinology, Diabetes and Obesity Malignant pheochromocytoma–paraganglioma …