Epstein–Barr virus (EBV) was the first human tumor virus being discovered and remains to
date the only human pathogen that can transform cells in vitro. 55 years of EBV research …

Dengue is one of the most important diseases transmitted by mosquitoes. Dengvaxia®, a
vaccine registered in several countries, cannot be administered to non-immune individuals …

Introduction The generation of an HIV-1 vaccine able to induce long-lasting protective
immunity remains a main challenge. Here, we aimed to modify next-generation soluble …

The use of heterologous immunization regimens and improved vector systems has led to
increases in immunogenicity of HIV-1 vaccine candidates in nonhuman primates. In order to …

Heterologous prime-boost strategies are of interest for HIV vaccine development. The order
of prime-boost components could be important for the induction of T cell responses. In this …

The HIV-1 immunogen and the design of the adjuvant formulations are both equally
important for the development of an effective HIV vaccine. Adjuvants work by numerous …

Different immunogens such as subunit, DNA or live viral-vectored vaccines against
Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the …

To date, six vaccine strategies have been evaluated in clinical trials for their efficacy at
inducing protective immune responses against HIV infection. However, only the ALVAC …

To control HIV infection there is a need for vaccines to induce broad, potent and long-term B
and T cell immune responses. With the objective to accelerate and maintain the induction of …

Despite the importance of the preventive vaccines sector against communicable diseases, it
did not take sufficient attention to it in terms of funding in recent years, but the emergence …