Red meat and processed meat intake is associated with a risk of colorectal cancer, a major
cause of death in affluent countries. Epidemiological and experimental evidence supports …

The lymphocyte function-associated antigen-1 (LFA-1)(also known as CD11a/CD18 and
αLβ2), is just one of many integrins in the human body, but its significance is derived from its …

Epidemiology shows that red and processed meat intake is associated with an increased
risk of colorectal cancer. Heme iron, heterocyclic amines, and endogenous N-nitroso …

In the era of molecular biology our understanding of subcellular processes that ultimately
lead to inflammatory bowel disease or colorectal cancer has widened considerably. The …

Colorectal neoplasia is the third most common cancer worldwide. Environmental factors
such as diet are known to be involved in the etiology of this cancer. Several epidemiological …

Introduction Recent studies have shown that epithelial-stromal interactions could play a role
in the development of colorectal cancer. Here, we investigated the role of fibroblasts in the …

Gastrin-releasing peptide (GRP) and its receptor (GRPR) act as morphogens when
expressed in colorectal cancer (CRC), promoting the assumption of a better differentiated …

Acquired resistance to apoptosis by tumor cells remains a major obstacle for cancer
treatment, and hence the analysis of resistance to apoptosis constitutes a major goal in the …

Aeginetia indica Linn.(Guan‐Jen‐Huang, GJH), a traditional Chinese herb, has the potential
to be an immunomodulatory agent. The purpose of this study was to explore the effect of …

Continuous and rapid renewal of the colonic epithelium is crucial to resist the plethora of
luminal deleterious agents. Subepithelial fibroblasts contribute to this turnover by regulating …