Genotypic and phenotypic composition of sickle cell disease in the Arab population-a systematic review

F Ata, A Rahhal, L Malkawi, P Iqbal… - Pharmacogenomics …, 2023 - Taylor & Francis
Sickle cell disease (SCD) is a genetic disease influenced by ethnicity and regional
differences in its clinical course. Recent advances in the management of SCD with newer …

Hemoglobin S/OARAB: Thirteen new cases and review of the literature

SA Zimmerman, EE O'Branski… - American journal of …, 1999 - Wiley Online Library
Abstract Hemoglobin S/OArab (Hb S/OArab) is a rare compound heterozygous
hemoglobinopathy characterized by the presence of two variant β‐globin chains: β6Glu→ …

Red cell life span in sickle cell-hemoglobin C disease with a note about sickle cell-hemoglobin O ARAB

PR McCurdy, L Mahmood, AS Sherman - 1975 - ashpublications.org
Red cell survival was measured in ten subjects with SC disease and one with SO Arab
(alpha 2 beta 2–121 glu yields lys) disease using both DF32p and 51Cr as tags. Red cell …

[PDF][PDF] Splenic size determination in sickle cell anaemia: an ultrasonographic study

AA Olatunji, PO Olatunji - East African medical journal, 2001 - ajol.info
Objectives: To examine the generally accepted concept of autosplenectomy in patients with
sickle cell anaemia, and determine the relationship between age, the steady state PCV and …

Genetic disorders in Sudan

MAM Salih - Genetic disorders among Arab populations, 2010 - Springer
Sudan is Africa's largest country in surface area (2,505,805 km 2). It constitutes more than
8% of the African continent and 1.7% of the world's total land (Fig. 20.1). It has boundaries …

Human haemoglobins and haemoglobinopathies in Arabia: hb O Arab in Saudi Arabia

MAF El-Hazmi, H Lehmann - Acta Haematologica, 1980 - karger.com
In the Arabian peninsula, haemoglobinopathîes, though very interesting, are still far from
being fairly established. With the exception of the eastern province of Saudi Arabia, where …

The interaction of hemoglobin O Arab with Hb S and β+ thalassemia among Israeli Arabs

EA Rachmilewitz, H Tamari, F Liff, Y Ueda, RL Nagel - Human genetics, 1985 - Springer
We have studied 105 individuals in the village of Jasser El Zarka in the Northern Coast of
Israel of whom 59% had at least one abnormal hemoglobin. Of the individuals studied 41 …

The super sickling haemoglobin HbS‐Oman: a study of red cell sickling, K+ permeability and associations with disease severity in patients heterozygous for HbA and …

HWM Al Balushi, Y Wali, M Al Awadi… - British Journal of …, 2017 - Wiley Online Library
Studying different sickle cell genotypes may throw light on the pathogenesis of sickle cell
disease (SCD). Here, the clinical profile, red cell sickling and K+ permeability in 29 SCD …

Molecular Detection of Hemoglobin O-Arab in the Sudanese Population

I Elbashir, TY Elsayed Yousif - International Journal of General …, 2023 - Taylor & Francis
Background and Purpose Sickle cell disease (SCD) is an inherited hemoglobin disease
affecting the red cells and causing hemolytic anemia. It is a very common, endemic disease …

Twelve families with Hb 0 Arab in the Burgas district of Bulgaria observations on sixteen examples of Hb 0 β° thalassaemia

KN Kantchev, BN Tcholakov, R Casey, H Lehmann… - Humangenetik, 1975 - Springer
Twelve families with Hb 0 Arab in the Burgas district of Bulgaria observations on sixteen
examples of Hb 0 β&#x00 Page 1 Humangenetik 26, 93--97 (1975) © by Springer-Verlag …