Recent advances in nanoparticle-based drug delivery systems for rheumatoid arthritis treatment

S Nasra, D Bhatia, A Kumar - Nanoscale advances, 2022 - pubs.rsc.org
Nanotechnology has increasingly emerged as a promising tool for exploring new
approaches, from treating complex conditions to early detection of the onset of multiple …

Nanomaterials manipulate macrophages for rheumatoid arthritis treatment

S Li, J Su, W Cai, J Liu - Frontiers in Pharmacology, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic, progressive, and systemic inflammatory autoimmune
disease, characterized by synovial inflammation, synovial lining hyperplasia and …

Preparation and in vitro evaluation of radiolabeled HA-PLGA nanoparticles as novel MTX delivery system for local treatment of rheumatoid arthritis

RM Trujillo-Nolasco, E Morales-Avila… - Materials Science and …, 2019 - Elsevier
Radiosynovectomy is a technique used to decrease inflammation of the synovial tissue by
intraarticular injection of a β-emitting radionuclide, such as 177 Lu, which is suitable for …

Targeted co-delivery biomimetic nanoparticles reverse macrophage polarization for enhanced rheumatoid arthritis therapy

X Zheng, X Yu, C Wang, Y Liu, M Jia, F Lei, J Tian… - Drug Delivery, 2022 - Taylor & Francis
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, which is characterized
by synovial inflammation and autoimmunity. The main cause of the disease is the imbalance …

Hyaluronic acid-functionalized bilosomes for targeted delivery of tripterine to inflamed area with enhancive therapy on arthritis

H Yang, Z Liu, Y Song, C Hu - Drug delivery, 2019 - Taylor & Francis
Arthritis treatment has been challenging because of low drug exposure to the articular cavity.
This study was intended to develop hyaluronic acid (HA)-functionalized bilosomes for …

89Zr-Labeled Multifunctional Liposomes Conjugate Chitosan for PET-Trackable Triple-Negative Breast Cancer Stem Cell Targeted Therapy

R Yang, M Lu, L Ming, Y Chen, K Cheng… - International journal …, 2020 - Taylor & Francis
Purpose Therapy for triple-negative breast cancer (TNBC) is a global problem due to lack of
specific targets for treatment selection. Cancer stem cells (CSCs) are responsible for tumor …

Exploring the applications of hyaluronic acid‐based nanoparticles for diagnosis and treatment of bacterial infections

M Mohammed, N Devnarain… - Wiley …, 2022 - Wiley Online Library
Hyaluronic acid (HA) has become a topic of significant interest in drug delivery research due
to its excellent properties, including biosafety, biodegradability, and nonimmunogenicity …

[HTML][HTML] Molecular mechanism of anti-cancer activity of the nano-drug C-PC/CMC-CD59sp NPs in cervical cancer

L Jiang, Y Wang, F Zhu, G Liu, H Liu, H Ji… - Journal of …, 2019 - ncbi.nlm.nih.gov
The novel tumor targeted nano-drug C-PC/CMC-CD59sp nanoparticles were constructed
with carbocymethyl chitosan (CMC), C-phycocyanin (C-PC) and CD59 specific ligand …

Co-Delivery of Teriflunomide and Methotrexate from Hydroxyapatite Nanoparticles for the Treatment of Rheumatoid Arthritis: In Vitro Characterization …

S Pandey, V Kumar, A Leekha, N Rai, FJ Ahmad… - Pharmaceutical …, 2018 - Springer
Purpose The present investigation was aimed at developing Teriflunomide (TEF) and
Methotrexate (MTX) loaded hydroxyapatite nanoparticles and increasing tolerability towards …

SNX5 suppresses clear cell renal cell carcinoma progression by inducing CD44 internalization and epithelial-to-mesenchymal transition

Q Zhou, J Li, C Ge, J Chen, W Tian, H Tian - Molecular Therapy-Oncolytics, 2022 - cell.com
Aberrant expression of SNX5 can contribute to tumorigenesis, invasion, and metastasis of
several human cancers. However, the clinicopathological and biological significance of …