Clathrin-mediated endocytosis (CME) is the major endocytic pathway in mammalian cells. It
is responsible for the uptake of transmembrane receptors and transporters, for remodeling …

Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …

Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

Nanomedicines employ multiple endocytic pathways to enter cells. Their following fate is
interesting, but it is not sufficient understood currently. This review introduces the endocytic …

Sporulation in Bacillus subtilis involves an asymmetric cell division followed by
differentiation into two cell types, the endospore and the mother cell. The endospore coat is …

Novel nanomaterials are being developed to improve diagnosis and therapy of diseases
through effective delivery of drugs, biopharmaceutical molecules and imaging agents to …

Background The size and complexity of conifer genomes has, until now, prevented full
genome sequencing and assembly. The large research community and economic …

The endosomal sorting complexes required for transport (ESCRTs) catalyse one of the most
unusual membrane remodelling events in cell biology. ESCRT-I and ESCRT-II direct …

The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …

The secretory pathway is responsible for the synthesis, folding, and delivery of a diverse
array of cellular proteins. Secretory protein synthesis begins in the endoplasmic reticulum …