Abstract The 4, 4′-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally
used as a potent anti-bacterial agent in clinical management of leprosy. For decades …

Scavenger receptor type BI (SR‐BI), the major receptor for high‐density lipoprotein (HDL)
mediates the delivery of cholesterol ester and cholesterol from HDL to the cell membrane …

Myocardial infarction (MI) is a critical condition that can happen with high doses or rapid
termination of beta blockers therapy. The study aimed to evaluate the potential anti-toxic …

Aims Acute lung injury (ALI) is a life-threatening clinical problem with high mortality rate and
limited treatments or preventive options that represents a major challenge for clinicians …

Background Acetaminophen (APAP) is a worldwide antipyretic as well as an analgesic
medication. It has been extensively utilized during the outbreak of coronavirus 2019 (COVID …

Ulcerative colitis (UC) is a chronic inflammatory life-threatening and premalignant disorder
with no cure that even might end up with surgical removal of a large section or even all of the …

Diacerein is an interleukin (IL)-1β inhibitor approved for osteoarthritis. This study aimed to
investigate the potential anti-fibrotic effect of diacerein against bile duct ligation (BDL) …

Background Heart failure is a common event in the course of hypertension. Recent studies
have highlighted the key role of the non-hemodynamic activity of angiotensin II (Ang II) in …

The present study aimed to identify the possible protective effect of diacerein (DIA) on
gentamicin (GNT)‐induced parotid toxicity in rats. DIA was administered in the presence and …

Hepatic ischemia-reperfusion (I/R) is an important cause of liver damage in many clinical
situations. Toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) is an inflammatory …