Since its first suggestion as possible option for liver radioembolization treatment, the
therapeutic isotope holmium-166 (166Ho) caught the experts' attention due to its imaging …

Radioembolization with 90 Y-loaded microspheres is increasingly used in the treatment of
primary and secondary liver cancer. Technetium-99 m macroaggregated albumin (MAA) …

Primary liver tumours (ie hepatocellular carcinoma (HCC) or intrahepatic
cholangiocarcinoma (ICC)) are among the most frequent cancers worldwide. However, only …

The aim of this standard operational procedure is to standardize the methodology employed
for the evaluation of pre-and post-treatment absorbed dose calculations in 90 Y microsphere …

Purpose As an alternative to technetium-99m-macroaggregated albumin (99m Tc-MAA), a
scout dose of holmium-166 (166 Ho) microspheres can be used prior to 166 Ho …

Over the years, a broad spectrum of applications of the radionuclide holmium-166 as a
medical isotope has been established. The isotope holmium-166 is attractive as it emits high …

Radioembolization is an established treatment for chemoresistant and unresectable liver
cancers. Currently, treatment planning is often based on semi-empirical methods, which …

Purpose To investigate hepatocellular carcinoma tumor dose-response characteristics
based on voxel-level absorbed doses (D) and biological effective doses (BED) using …

Purpose Radioembolization of liver metastases of neuroendocrine neoplasms (NEN) has
shown promising results; however, the current literature is of limited quality. A large …

Holmium microspheres have recently become available in the European market as the third
type of microspheres for radioembolization of unresectable liver malignancies. Holmium …