An overview of influenza A virus genes, protein functions, and replication cycle highlighting important updates

RP Chauhan, ML Gordon - Virus Genes, 2022 - Springer
The recent research findings on influenza A virus (IAV) genome biology prompted us to
present a comprehensive overview of IAV genes, protein functions, and replication cycle …

[HTML][HTML] Potential of diterpene compounds as antivirals, a review

AP Wardana, NS Aminah, M Rosyda, MI Abdjan… - Heliyon, 2021 - cell.com
Viruses cause widely transmitted diseases resulting in pandemic conditions. Currently, the
world is being hit by the Covid-19 pandemic caused by the SAR-CoV-2 infection. Countries …

[HTML][HTML] How influenza virus uses host cell pathways during uncoating

EA Moreira, Y Yamauchi, P Matthias - Cells, 2021 - mdpi.com
Influenza is a zoonotic respiratory disease of major public health interest due to its pandemic
potential, and a threat to animals and the human population. The influenza A virus genome …

[HTML][HTML] Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B

M Schoof, L Wang, JZ Cogan, RE Lawrence… - Nature …, 2021 - nature.com
Viral infection triggers activation of the integrated stress response (ISR). In response to viral
double-stranded RNA (dsRNA), RNA-activated protein kinase (PKR) phosphorylates the …

[HTML][HTML] Comparing influenza virus biology for understanding influenza d virus

RM Skelton, VC Huber - Viruses, 2022 - mdpi.com
The newest type of influenza virus, influenza D virus (IDV), was isolated in 2011. IDV
circulates in several animal species worldwide, causing mild respiratory illness in its natural …

[HTML][HTML] The potential of cannabinoids and inhibitors of endocannabinoid degradation in respiratory diseases

A Kicman, A Pędzińska-Betiuk, H Kozłowska - European Journal of …, 2021 - Elsevier
The global incidence of respiratory diseases and complications is increasing. Therefore,
new methods of treatment, as well as prevention, need to be investigated. A group of …

[HTML][HTML] Diversity and complexity of internally deleted viral genomes in influenza a virus subpopulations with enhanced interferon-inducing phenotypes

A Ghorbani, JM Ngunjiri, G Rendon, CB Brooke… - Viruses, 2023 - mdpi.com
Influenza A virus (IAV) populations harbor large subpopulations of defective-interfering
particles characterized by internally deleted viral genomes. These internally deleted …

[HTML][HTML] Protective versus Pathogenic Type I Interferon Responses during Virus Infections

KI Jung, S McKenna, V Vijayamahantesh, Y He… - Viruses, 2023 - mdpi.com
Following virus infections, type I interferons are synthesized to induce the expression of
antiviral molecules and interfere with virus replication. The importance of early antiviral type I …

[HTML][HTML] Role of Influenza A virus protein NS1 in regulating host nuclear body ND10 complex formation and its involvement in establishment of viral pathogenesis

U Das, M Chawla-Sarkar, SR Gangopadhyay, S Dey… - Plos one, 2024 - journals.plos.org
Influenza viral infection is a seasonal infection which causes widespread acute respiratory
issues among humans globally. This virus changes its surface receptor composition to …

[HTML][HTML] RNA-targeted therapies and high-throughput screening methods

S Zhu, S Rooney, G Michlewski - International Journal of Molecular …, 2020 - mdpi.com
RNA-binding proteins (RBPs) are involved in regulating all aspects of RNA metabolism,
including processing, transport, translation, and degradation. Dysregulation of RNA …