Affinely adjustable robust optimization for radiation therapy under evolving data uncertainty via semi-definite programming

V Jeyakumar, G Li, D Woolnough, H Wu - Optimization, 2024 - Taylor & Francis
Static robust optimization has played an important role in radiotherapy, where the decisions
aim to safeguard against all possible realizations of uncertainty. However, it may lead to …

A new dual-based cutting plane algorithm for nonlinear adjustable robust optimization

A Khademi, A Marandi… - Journal of Global …, 2024 - Springer
This paper explores a class of nonlinear Adjustable Robust Optimization (ARO) problems,
containing here-and-now and wait-and-see variables, with uncertainty in the objective …

Robust Radiotherapy Planning with Spatially Based Uncertainty Sets

N Goldberg, M Langer, S Shtern - IISE Transactions, 2024 - Taylor & Francis
Radiotherapy treatment planning is a challenging large-scale optimization problem plagued
by uncertainty. Following the robust optimization methodology, we propose a novel, spatially …

[PDF][PDF] Large-Scale Optimization Approaches for Radiation Therapy

D Ripsman - 2024 - uwspace.uwaterloo.ca
Radiation therapy treatment planning (RTTP) is a medically important, multistage clinical
problem that poses a number of challenges in practice. This daily clinical task is full of highly …

Nonlinear Adjustable Robust Optimization

A Khademi - 2024 - hal.science
Robust Optimization (RO) is a popular approach for dealing with uncertain data in
optimization. In static robust optimization, decision variables represent here-and-now …

Optimal interventions in robust optimization with time-dependent uncertainty

S Dabadghao, A Marandi, A Roy - Available at SSRN 3624421, 2021 - papers.ssrn.com
Uncertainties can be time-dependent, particularly in areas such as cancer radiotherapy
planning and maintenance scheduling, where the condition of the patient (or system) can …