Single-molecule localization microscopy
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
Improving the hole picture: towards a consensus on the mechanism of nuclear transport
Nuclear pore complexes (NPCs) mediate the exchange of materials between the
nucleoplasm and cytoplasm, playing a key role in the separation of nucleic acids and …
nucleoplasm and cytoplasm, playing a key role in the separation of nucleic acids and …
Quality control mechanisms that protect nuclear envelope identity and function
PJ Mannino, CP Lusk - Journal of Cell Biology, 2022 - rupress.org
The nuclear envelope (NE) is a specialization of the endoplasmic reticulum with distinct
biochemistry that defines inner and outer membranes connected at a pore membrane that …
biochemistry that defines inner and outer membranes connected at a pore membrane that …
Comparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope
The nuclear envelope (NE) is a subdomain of the ER with prominent roles in nuclear
organization, which are largely mediated by its distinctive protein composition. We …
organization, which are largely mediated by its distinctive protein composition. We …
Shared and distinctive neighborhoods of emerin and lamin B receptor revealed by proximity labeling and quantitative proteomics
LC Cheng, X Zhang, K Abhinav… - Journal of Proteome …, 2022 - ACS Publications
Emerin and lamin B receptor (LBR) are abundant transmembrane proteins of the nuclear
envelope that are concentrated at the inner nuclear membrane (INM). Although both …
envelope that are concentrated at the inner nuclear membrane (INM). Although both …
High-speed super-resolution imaging of rotationally symmetric structures using SPEED microscopy and 2D-to-3D transformation
Various super-resolution imaging techniques have been developed to break the diffraction-
limited resolution of light microscopy. However, it still remains challenging to obtain three …
limited resolution of light microscopy. However, it still remains challenging to obtain three …
[HTML][HTML] Enhancers on the edge—How the nuclear envelope controls gene regulatory elements
R Czapiewski, EC Schirmer - Current Opinion in Genetics & Development, 2024 - Elsevier
Highlights●The nuclear envelope (NE) contributes to 3D genome organization regulatory
control.●NE control of their localization affects the function of genes, enhancers, and …
control.●NE control of their localization affects the function of genes, enhancers, and …
Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor
T Tiago, B Hummel, FF Morelli, V Basile, J Vinet… - Cell death & …, 2021 - nature.com
One of the critical events that regulates muscle cell differentiation is the replacement of the
lamin B receptor (LBR)-tether with the lamin A/C (LMNA)-tether to remodel transcription and …
lamin B receptor (LBR)-tether with the lamin A/C (LMNA)-tether to remodel transcription and …
STING nuclear partners contribute to innate immune signaling responses
CR Dixon, P Malik, JI de Las Heras, N Saiz-Ros… - Iscience, 2021 - cell.com
Summary STimulator of INterferon Genes (STING) is an adaptor for cytoplasmic DNA
sensing by cGAMP/cGAS that helps trigger innate immune responses (IIRs). Although …
sensing by cGAMP/cGAS that helps trigger innate immune responses (IIRs). Although …
Unveiling the complexity: Assessing models describing the structure and function of the nuclear pore complex
The nuclear pore complex (NPC) serves as a pivotal subcellular structure, acting as a
gateway that orchestrates nucleocytoplasmic transport through a selectively permeable …
gateway that orchestrates nucleocytoplasmic transport through a selectively permeable …