Bladder cancer is one of the most common carcinomas in the human urinary system
worldwide. Loperamide, known as an antidiarrheal drug, exerts anti-tumor activities against …

Abstract Human carboxylesterase 2 (hCES2) is an enzyme that metabolizes irinotecan to SN-
38, a toxic metabolite considered a significant source of side effects (lethal delayed …

With a growing population of people living with and beyond cancer, a larger portion of
cancer research has shifted to ensuring that these people not only survive but survive well …

Background: Liu Jun An Wei formula (LJAW), derived from “Liu Jun Zi Decoction”, is a
classical prescription of Tradition Chinese Medicine and has been used for the treatment of …

Alternative animal models have become increasingly necessary due to legal regulations
aimed at reducing the use of laboratory animals. Invertebrates are gaining in importance …

Background Measuring quality indicators (QI's) is a tool to improve the quality of care. The
aim of this study was to evaluate the acceptability of 36 QI's, defined after a literature search …

Purpose Chemotherapy-induced diarrhoea (CID) is a common, but often underreported
problem in patients with breast cancer that has a profound effect on quality of life. It is best …

Background Chemotherapy-induced diarrhea (CID) is one of the side effects of
chemotherapy. Diarrhea not only affects the overall treatment effectiveness but also reduces …

The World Health Organization (WHO) defines adverse drug reactions (ADRs) as “Any
response to a drug which is noxious and unintended, and which occurs at doses normally …

Diarrhea in patients with cancer is a well-known phenomenon with clear guidelines for
prevention and management. However, it remains a condition with poorly explored …