Human matrix metalloproteinases (MMPs) belong to the M10 family of the MA clan of
endopeptidases. They are ubiquitarian enzymes, structurally characterized by an active site …

Matrix metalloproteinases (MMPs) are identifiable members of proteolytic enzymes that can
degrade a wide range of proteins in the extracellular matrix (ECM). MMPs can be …

This book is the third volume of the 4th Edition of the WHO series on histological and genetic
typing of human tumours. It is an authoritative, concise reference book providing an …

Background: Smoking has been related to esophageal and gastric cardia adenocarcinoma,
but the magnitude of the association is uncertain. Methods: We conducted a meta-analysis …

Background Tobacco smoking strongly increases risk of esophageal squamous cell
carcinoma and moderately increases risk of esophageal adenocarcinoma. How smoking …

Matrix metalloproteinase (MMP) comprises a family of zinc-dependent endopeptidases that
degrade various components of the extracellular matrix (ECM) and basement membrane …

In the last years, the extracellular matrix (ECM) has been reported as playing a relevant role
in esophageal cancer (EC) development, with this compartment being related to several …

The present invention relates to peptides, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the …

The process of carcinogenesis is tightly regulated by antioxidant enzymes and matrix
degrading enzymes, namely, matrix metalloproteinases (MMPs). Degradation of …

Abstract Background Matrix metalloproteases (MMPs) are proteolytic enzymes that
contribute to all stages of tumour progression, including the later stages of invasion and …