Atypical BSE is an invariably fatal neurologic disease of cattle caused by misfolded prion
proteins with different conformations than those associated with classical BSE. Evidence …

Occurring for the first time in 1986 in the United Kingdom, bovine spongiform
encephalopathy (BSE), the so-called “mad-cow disease”, has had unprecedented …

Each known abnormal prion protein (PrPSc) is considered to have a specific range and
therefore the ability to infect some species and not others. Consequently, some species …

Bovine spongiform encephalopathy (BSE) created a global European crisis in the 1980s
and 90s, with very serious health and economic implications. Classical BSE now appears to …

This paper describes the generation, characterisation and potential applications of a panel
of novel anti-prion protein monoclonal antibodies (mAbs). The mAbs were generated by …

Since 2004 it become clear that atypical bovine spongiform encephalopthies (BSEs) exist in
cattle. Whenever their detection has relied on active surveillance plans implemented in …

Prions result from a drastic conformational change of the host-encoded cellular prion protein
(PrP), leading to the formation of β-sheet–rich, insoluble, and protease-resistant self …

Bovine spongiform encephalopathy (BSE) is caused by different prion strains that are
discriminated by the molecular characteristics of the pathological prion protein. In 2011 …

BSE is a transmissible spongiform encephalitis (TSE) caused by prion protein.
Transmissible spongiform encephalopathies (TSEs) are characterised by fatal …

Bovine spongiform encephalopathy (BSE) is an invariably fatal prion disease of cattle. The
identification of the zoonotic potential of BSE prompted safety officials to initiate surveillance …