Cancer multidrug-resistance reversal by ABCB1 inhibition: A recent update
K Engle, G Kumar - European journal of medicinal chemistry, 2022 - Elsevier
Chemotherapy is one of the most common treatments for cancer that uses one or more anti-
cancer drugs as a part of the standardized chemotherapy regimen. Cytotoxic chemicals …
cancer drugs as a part of the standardized chemotherapy regimen. Cytotoxic chemicals …
Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections
Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …
effector immune defense molecules in multicellular organisms. AMPs exert their …
Bacterial resistance to antimicrobial agents
Bacterial pathogens as causative agents of infection constitute an alarming concern in the
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …
[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria
Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …
Distribution and spread of the mobilised RND efflux pump gene cluster tmexCD-toprJ in clinical Gram-negative bacteria: a molecular epidemiological study
N Dong, Y Zeng, Y Wang, C Liu, J Lu, C Cai… - The Lancet …, 2022 - thelancet.com
Summary Background TMexCD1-TOprJ1, which is associated with phenotypic resistance to
multiple classes of antibiotics, is a transmissible resistance-nodulation-division (RND) family …
multiple classes of antibiotics, is a transmissible resistance-nodulation-division (RND) family …
A comprehensive review of nanoparticles for oral delivery in food: biological fate, evaluation models, and gut microbiota influences
Edible nanoparticles are being developed for the oral delivery of nutrients to improve human
health and well-being. Because of the extremely demanding conditions foods experience …
health and well-being. Because of the extremely demanding conditions foods experience …
Inhibition of multidrug efflux pumps belonging to the major facilitator superfamily in bacterial pathogens
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are
causative agents of infectious disease, and they thus constitute a serious concern for public …
causative agents of infectious disease, and they thus constitute a serious concern for public …
Macrophage targeted iron oxide nanodecoys augment innate immunological and drug killings for more effective Mycobacterium Tuberculosis clearance
L Shen, K Liao, E Yang, F Yang, W Lin, J Wang… - Journal of …, 2023 - Springer
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, is still one of the
top killers worldwide among infectious diseases. The escape of Mtb from immunological …
top killers worldwide among infectious diseases. The escape of Mtb from immunological …
A 2.8 Å Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase
Since 2000, some thirteen quinolones and fluoroquinolones have been developed and
have come to market. The quinolones, one of the most successful classes of antibacterial …
have come to market. The quinolones, one of the most successful classes of antibacterial …
A multifunctional polymeric micelle for targeted delivery of paclitaxel by the inhibition of the P-glycoprotein transporters
P-glycoprotein (P-gP) efflux-mediated multidrug resistance is a fundamental aspect of
chemotherapeutic failure in oncology. The current study aims to deliver paclitaxel (PTX) …
chemotherapeutic failure in oncology. The current study aims to deliver paclitaxel (PTX) …