Given the critical role of liver mechanics in regulating cell response and directing the
development of tissue fibrosis, accurately characterising its mechanical behaviour is of …

Cells perceive the physical cues such as perturbations of extracellular matrix (ECM)
stiffness, and translate these stimuli into biochemical signals controlling various aspects of …

Aberrant variations in angiogenesis have been observed in tumor tissues with abnormal
stiffness of extracellular matrix (ECM). However, it remains largely unclear how ECM …

Vascular smooth muscle cell (vSMC) is highly plastic as its phenotype can change in
response to mechanical cues inherent to the extracellular matrix (ECM). VSMC may be …

Alginate-based hydrogels are extensively used matrices for cell encapsulation, but they
need to be modified to recapitulate chemical, microstructural, and mechanical properties of …

Small intestinal submucosa (SIS) is a widely concerned acellular material for reconstructing
tissue defects, but during the restoration of abdominal wall, it has been restricted due to the …

Precise and accurate measurement of viscoelastic mechanical properties becomes
increasingly challenging as sample stiffness decreases to elastic moduli< 1 kPa, largely due …

Objective—Platelet-and fibrin-dependent thrombus formation is regulated by blood flow and
exposure of collagen and tissue factor. However, interactions between these blood-borne …

Biological organisms are inherently complex. Although investigations of the function and
design of living organisms have existed since the dawn of science, only in recent years have …

In spite of tremendous advances made in the comprehension of mechanotransduction,
implementation of mechanobiology assays remains challenging for the broad community of …