Transcriptional Regulation: Flipping the Myc switch: Current Biology Skip to Main Content
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Immature B cells migrate to the spleen where they differentiate into mature cells. This final
maturation step is crucial to enable B cells to become responsive to antigens and to …

INO2 and INO4 are two genes in Saccharomyces cerevisiae that encode basic helix-loop-
helix (bHLH) transcription factors which regulate the phospholipid biosynthetic genes. Ino2p …

Sin3 corepressor and Rpd3 histone deacetylase negatively regulate a diverse set of genes
in yeast. We show that both Sin3 and Rpd3 can be recruited the promoters of their target …

Nuclear receptors are ligand-dependent transcription factors which can either positively or
negatively regulate target gene transcription by association with either coactivators or …

A cell responds to the extracellular environment by transducing signals from the cell surface
to the nucleus. This results in chances that eventually affect gene expression. This process …

1.2 Modif, rcation of histones and regulation of transcription 1.3 Histone acetylation and
deacetylation 1.3. I Histone acetylation and transcriptional activation 1.3. 2 Histone …