Abstract Treatment decisions for patients with chronic lymphocytic leukemia (CLL) are
dependent on symptoms and classification into high-, medium-, or low-risk categories. The …

In the last few decades, there has been a growing interest in Bruton's tyrosine kinase (BTK)
and the compounds that target it. BTK is a downstream mediator of the B-cell receptor (BCR) …

Chronic lymphocytic leukemia (CLL) still represents an incurable disorder that may progress
to other more aggressive types of cancer despite the available therapy and the development …

Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of neoplastic B
lymphocytes with high levels of Wnt5a in the plasma. Currently, the cell source of Wnt5a …

The continuous improvement of life expectancy of patients with chronic lymphocytic
leukemia (CLL) has resulted in increased risk of second primary malignancy that potentially …

Introduction While prognosis for patients with chronic lymphocytic leukemia (CLL) has
improved over time in younger adults, only modest improvements have occurred in older …

A leucemia linfocítica crónica é uma neoplasia hematológica linfo proliferativa que resulta
da proliferação e acumulação de linfócitos B monoclonais. É a doença hematológica mais …