Signal amplification in electrochemical DNA biosensors using target-capturing DNA origami tiles

P Williamson, P Piskunen, H Ijäs, A Butterworth… - ACS …, 2023 - ACS Publications
Electrochemical DNA (e-DNA) biosensors are feasible tools for disease monitoring, with
their ability to translate hybridization events between a desired nucleic acid target and a …

On-site and quantitative detection of trace methamphetamine in urine/serum samples with a surface-enhanced Raman scattering-active microcavity and rapid …

W Fang, B Zhang, FY Han, ZN Qin, YQ Feng… - Analytical …, 2020 - ACS Publications
Here, it reports a high-throughput detection method for reliably quantitative analysis of illegal
drugs in complex biological samples by means of a surface-enhanced Raman scattering …

How Surfaces Affect Hybridization Kinetics

E Treasurer, R Levicky - The Journal of Physical Chemistry B, 2021 - ACS Publications
Hybridization between nucleic acid strands immobilized on a solid support with partners in
solution is widely practiced in bioanalytical technologies and materials science. An …

Improved Thermal Stability and Homogeneity of Low Probe Density DNA SAMs Using Potential-Assisted Thiol-Exchange Assembly Methods

T Ma, D Bizzotto - Analytical Chemistry, 2021 - ACS Publications
Methods for producing DNA SAM-based sensors with improved thermal stability and control
over the homogeneity of low DNA probe density will enable advanced sensor development …

An electricity-fluorescence double-checking biosensor based on graphene for detection of binding kinetics of DNA hybridization

W Yue, C Tang, C Wang, C Bai, S Liu, X Xie, H Hua… - RSC …, 2017 - pubs.rsc.org
In this paper, the study of an electricity-fluorescence double-checking biosensor and
detection system has been presented. The fabrication of the double-checking biosensor was …

Introducing an SPRi-based titration assay using aptamers for the detection of Legionella pneumophila

M Saad, FR Castiello, SP Faucher… - Sensors and Actuators B …, 2022 - Elsevier
Legionella are waterborne bacteria and the causative agents behind a severe respiratory
disease known as Legionnaires Disease (LD). Standard ISO-certified methods to detect …

Interplay of electrostatic repulsion and surface grafting density on surface-mediated DNA hybridization

JC Traeger, DK Schwartz - Journal of colloid and interface science, 2020 - Elsevier
Single-molecule Förster Resonance Energy Transfer was used to observe the adsorption of
fluorescently-labeled “target” DNA oligonucleotides and their association and hybridization …

Polyadenine-mediated immobilization of aptamers on a gold substrate for the direct detection of bacterial pathogens

WW Wang, X Han, LQ Chu - Analytical Sciences, 2019 - Springer
Nucleic acid aptamers have been widely used as synthetic probes for bioanalytical
applications. Herein, we carried out a detailed study on the immobilization of a series of …

Correlated Hybrid DNA Structures Explored by the oxDNA Model

YP Qiao, CL Ren - Langmuir, 2023 - ACS Publications
Thermodynamically, perfect DNA hybridization can be formed between probes and their
corresponding targets due to the favorable energy. However, this is not the case …

Preparation of a poly (PEGDA‐co‐GMA) thin hydrogel matrix for oligonucleotide microarray applications

Y Qi, K Li, C Zhao, Y Ma, W Yang - Journal of Chemical …, 2021 - Wiley Online Library
BACKGROUND Fabricating oligonucleotide microarrays with high immobilization efficiency
and sensitivity by a simple surface modification route remains highly desirable in the biochip …