[HTML][HTML] KRAS as a key oncogene in the clinical precision diagnosis and treatment of pancreatic cancer

M Dai, S Chen, X Teng, K Chen, W Cheng - Journal of Cancer, 2022 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors, with a 5-
year survival rate of less than 10%. At present, the comprehensive treatment based on …

ERK inhibition in glioblastoma is associated with autophagy activation and tumorigenesis suppression

K Yang, L Luan, X Li, X Sun, J Yin - Journal of neuro-oncology, 2022 - Springer
Purpose Autophagy-dependent tumorigenic growth is one of the most commonly reported
molecular mechanisms in glioblastoma (GBM) progression. However, the mechanistic …

Matairesinol induces mitochondrial dysfunction and exerts synergistic anticancer effects with 5-fluorouracil in pancreatic cancer cells

W Lee, G Song, H Bae - Marine drugs, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of cancer
and exhibits a devastating 5-year survival rate. The most recent procedure for the treatment …

[HTML][HTML] Aminoacylase 1 (ACY-1) mediates the proliferation and migration of neuroblastoma cells in humans through the ERK/transforming growth factor β (TGF-β) …

Z Chen, J Gao, J Sun, Z Wu, B Wang - Medical Science Monitor …, 2021 - ncbi.nlm.nih.gov
Background Aminoacylase 1 (ACY-1) is a cytosolic enzyme that catalyzes amino acid
deacylation and has been reported to participate in various human diseases. However, the …

Atsparumo 5-fluoruracilui ir oksaliplatinai molekulinių mechanizmų tyrimai žmogaus kolorektalinės karcinomos ląstelėse

V Žitkutė - 2024 - epublications.vu.lt
Abstract [eng] Colorectal cancer (CRC) is the second leading cause of death worldwide.
Advanced CRC is treated with a combination of the chemotherapy drugs 5-fluorouracil (5 …

[PDF][PDF] ALLEY PROOF

AS Chen - Med Sci Monit, 2020 - pdfs.semanticscholar.org
Background: Aminoacylase 1 (ACY-1) is a cytosolic enzyme that catalyzes amino acid
deacylation and has been reported to participate in various human diseases. However, the …