Bioactivities and green advanced extraction technologies of ginger oleoresin extracts: A review

MSH Kamaruddin, GH Chong, NM Daud… - Food Research …, 2023 - Elsevier
Zingiber officinale Roscoe is an excellent source of bioactive compounds, mainly gingerols
and shogaols compounds, that associated with various bioactivities including antioxidant …

Promising influences of zingerone against natural and chemical toxins: A comprehensive and mechanistic review

S Shamsabadi, Y Nazer, J Ghasemi, E Mahzoon… - Toxicon, 2023 - Elsevier
Zingerone is a flavor phytochemical present in ginger, a flowering plant belonging to the
Zingiberaceae family used as a condiment and herbal remedy. It possesses anti …

[HTML][HTML] Nephroprotective effect of naringin in methotrexate induced renal toxicity in male rats

H Elsawy, AM Alzahrani, M Alfwuaires… - Biomedicine & …, 2021 - Elsevier
Highlights•Naringin induced a marked decrease of renal injury markers in MTX-treated
rats.•Naringin protected against redox imbalance of renal tissue in MTX-treated …

Laminaria japonica fucoidan ameliorates cyclophosphamide‐induced liver and kidney injury possibly by regulating Nrf2/HO‐1 and TLR4/NF‐κB signaling pathways

S Tian, X Jiang, Y Tang, T Han - Journal of the Science of Food …, 2022 - Wiley Online Library
BACKGROUND During clinical practice, cyclophosphamide (CTX) can lead to liver and
kidney injury in vivo. In this study, we established a liver and kidney injury model by injecting …

Methotrexate-induced alteration of renal Aquaporins 1 and 2, oxidative stress and tubular apoptosis can be attenuated by Omega-3 fatty acids supplementation

MSE El-Agawy, AMM Badawy, MR Rabei… - International Journal of …, 2022 - mdpi.com
Methotrexate (MTX) is a potent anti-cancer drug, commonly associated with nephrotoxicity
via the induction of oxidative stress and apoptosis with alteration of renal water channel …

Tyrosol improves ovalbumin (OVA)-induced asthma in rat model through prevention of airway inflammation

M Cellat, M Kuzu, CT İşler, M Etyemez… - Naunyn-Schmiedeberg's …, 2021 - Springer
Asthma is an inflammatory disease that affects many people around the world, especially
persons at paediatric age group. The effectiveness of tyrosol, a natural phenolic compound …

Dose-dependent renoprotective effect of vanillic acid on methotrexate-induced nephrotoxicity via its anti-apoptosis, antioxidant, and anti-inflammatory properties

N Amini, MH Shoshtari, F Nejaddehbashi… - Naunyn-Schmiedeberg's …, 2024 - Springer
Methotrexate-induced nephrotoxicity is a medical emergency which is associated with a
variety of side effects. Vanillic acid (VA), as an antioxidant, removes free radical oxygen to …

Naringin protects mice from D-galactose-induced lung aging and mitochondrial dysfunction: Implication of SIRT1 pathways

AAA Salama, NN Yassen, HM Mansour - Life Sciences, 2023 - Elsevier
Aim Aging is the leading risk factor for diminishing lung function, as well as injury and lung
disorder. The target of our research was to examine the potential protective effect of naringin …

Naringin prevents diabetic nephropathy in rats through blockage of oxidative stress and attenuation of the mitochondrial dysfunction

A Pérez, J Mukdsi, L Valdez… - Canadian Journal of …, 2023 - cdnsciencepub.com
We have studied the effects of naringin (NAR), a flavonoid from citric fruits, on morphology,
ultrastructure and function of the kidney in streptozotocin (STZ)-induced diabetic rats. Two …

Salvadora persica extract attenuates cyclophosphamide-induced hepatorenal damage by modulating oxidative stress, inflammation and apoptosis in rats

T Bokhary, B Refaat, ES Bakr, S Baz, B Rajab… - Journal of integrative …, 2022 - Elsevier
Objective Salvadora persica (SP) is used as a food additive and is a common ingredient in
folk medicine. This study investigates the antioxidant, anti-inflammatory, and beneficial …