In agro-ecosystem, plant pathogens hamper food quality, crop yield, and global food security. Manipulation of naturally occurring defense mechanisms in host plants is an …
Y Chen, T Lu, U Pettersson-Kymmer, ID Stewart… - Nature …, 2023 - nature.com
Metabolic processes can influence disease risk and provide therapeutic targets. By conducting genome-wide association studies of 1,091 blood metabolites and 309 metabolite …
The serum metabolome contains a plethora of biomarkers and causative agents of various diseases, some of which are endogenously produced and some that have been taken up …
Few studies have explored the impact of rare variants (minor allele frequency< 1%) on highly heritable plasma metabolites identified in metabolomic screens. The Finnish …
Y Hasin, M Seldin, A Lusis - Genome biology, 2017 - Springer
High-throughput technologies have revolutionized medical research. The advent of genotyping arrays enabled large-scale genome-wide association studies and methods for …
Metabolic anomalies contribute to tissue dysfunction. Current metabolism research spans from organelles to populations, and new technologies can accommodate investigation …
Recent advances in high-throughput technologies have enabled the profiling of multiple layers of a biological system, including DNA sequence data (genomics), RNA expression …
J Xia, IV Sinelnikov, B Han, DS Wishart - Nucleic acids research, 2015 - academic.oup.com
Abstract MetaboAnalyst (www. metaboanalyst. ca) is a web server designed to permit comprehensive metabolomic data analysis, visualization and interpretation. It supports a …
RW McGarrah, SB Crown, GF Zhang, SH Shah… - Circulation …, 2018 - Am Heart Assoc
Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics, one of the newer omics technologies, has emerged as a powerful tool for defining changes …