Traditional ophthalmic drugs, such as eye drops, gels and ointments, are accompanied by
many problems, including low bioavailability and potential drug side effects. Innovative …

SUMMARY Human alphaherpesvirus 1 (HSV-1) is a highly successful neurotropic pathogen
that primarily infects the epithelial cells lining the orofacial mucosa. After primary lytic …

Herpes simplex virus type 1 (HSV-1) is a highly successful pathogen that primarily infects
epithelial cells of the orofacial mucosa. After initial lytic replication, HSV-1 enters sensory …

Keratitis is a disease characterized by inflammation of the cornea caused by different
pathogens. It can cause serious visual morbidity if not treated quickly. Depending on the …

Herpes simplex virus type 1 (HSV-1) is a prevalent human pathogen. HSV-1 genomes
persist in trigeminal ganglia neuronal nuclei as chromatinized episomes, while epithelial …

Neutrophils are the most abundant circulating innate immune cells and comprise the first
immune defense line, as they are the most rapidly recruited cells at sites of infection or …

Corneal Ulcer - StatPearls - NCBI Bookshelf US flag An official website of the United States
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …

The human oral cavity contains a plethora of habitats and tissue environments, such as
teeth, tongue, and gingiva, which are home to a rich microbial flora including bacteria, fungi …

Ocular diseases are increasingly influencing people's quality of life. Complicated
inflammatory mechanisms involved in the pathogenic process of ocular diseases make …

Introduction Herpes simplex keratitis (HSK) is a blinding disease caused by corneal infection
of Herpes simplex virus type 1 (HSV-1). Effective clearance of HSV-1 from the infected …