Suboptimal viral suppression rates among HIV-infected children in low-and middle-income countries: a meta-analysis

RS Boerma, TS Boender, AP Bussink… - Clinical infectious …, 2016 - academic.oup.com
Background The 90-90-90 goal to achieve viral suppression in 90% of all human
immunodeficiency virus (HIV)–infected people on antiretroviral treatment (ART) is especially …

A superiority of viral load over CD4 cell count when predicting mortality in HIV patients on therapy

C Shoko, D Chikobvu - BMC infectious diseases, 2019 - Springer
Background CD4 cell count has been identified to be an essential component in monitoring
HIV treatment outcome. However, CD4 cell count monitoring sometimes fails to predict …

The need for second-line antiretroviral therapy in adults in sub-Saharan Africa up to 2030: a mathematical modelling study

J Estill, N Ford, L Salazar-Vizcaya, AD Haas… - The Lancet …, 2016 - thelancet.com
Background The number of patients in need of second-line antiretroviral drugs is increasing
in sub-Saharan Africa. We aimed to project the need of second-line antiretroviral therapy in …

Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

MB Shapiro, T Cheever, DC Malherbe… - Nature …, 2020 - nature.com
Vertical transmission accounts for most human immunodeficiency virus (HIV) infection in
children, and treatments for newborns are needed to abrogate infection or limit disease …

The role of HIV viral load in mathematical models of HIV transmission and treatment: a review

T Glass, L Myer, M Lesosky - BMJ Global Health, 2020 - gh.bmj.com
Introduction HIV viral load (VL) is accepted as a key biomarker in HIV transmission and
pathogenesis. This paper presents a review of the role of VL testing in mathematical models …

Differences in virologic and immunologic response to antiretroviral therapy among HIV-1-infected infants and children

KH Ásbjörnsdóttir, JP Hughes, D Wamalwa, A Langat… - Aids, 2016 - journals.lww.com
Background: Virologic and immunologic responses to antiretroviral treatment (ART) in
infants may differ from older children due to immunologic, clinical, or epidemiologic …

Drug resistance testing through remote genotyping and predicted treatment options in human immunodeficiency virus type 1 infected Tanzanian subjects failing first or …

J Svärd, S Mugusi, D Mloka, U Neogi, G Meini… - PloS one, 2017 - journals.plos.org
Introduction Antiretroviral therapy (ART) has been successfully introduced in low-middle
income countries. However an increasing rate of ART failure with resistant virus is reported …

Association of CD4 cell counts and viral load with cystatin C level in children with human immunodeficiency virus (HIV) infection

W Rostania, A Alam, D Hilmanto - Paediatrica …, 2023 - paediatricaindonesiana.org
Background The ease of access to antiretroviral therapy (ART) has improved both survival
rate and comorbidities in patients with human immunodeficiency virus (HIV) infection …

Virologic response of treatment experienced HIV-infected Ugandan children and adolescents on NNRTI based first-line regimen, previously monitored without viral …

P Kibalama Ssemambo, MG Nalubega-Mboowa… - BMC pediatrics, 2021 - Springer
Abstract Background Many HIV-infected African children gained access to antiretroviral
treatment (ART) through expansion of PEPFAR programs since 2004 and introduction of …

HIV-1 integrase drug-resistance mutations in Iranian treatment-experienced HIV-1-infected patients

A Marjani, F Bokharaei-Salim, F Jahanbakhshi… - Archives of …, 2020 - Springer
The latest class of antiretrovirals (ARVs), including integrase strand transfer inhibitors
(INSTIs), has been demonstrated to be effective for antiretroviral therapy (ART). Despite all …