A comprehensive literature review and expert consensus statement on therapeutic drug monitoring of biologics in inflammatory bowel disease

AS Cheifetz, MT Abreu, W Afif, RK Cross… - Official journal of the …, 2021 - journals.lww.com
Therapeutic drug monitoring (TDM) of biologics is a rapidly evolving field. We aimed to
provide a consensus statement regarding the clinical utility of TDM for biologics in …

[HTML][HTML] Appropriate therapeutic drug monitoring of biologic agents for patients with inflammatory bowel diseases

K Papamichael, AS Cheifetz, GY Melmed… - Clinical …, 2019 - Elsevier
Background & Aims Therapeutic drug monitoring (TDM) is widely available for biologic
therapies in patients with inflammatory bowel disease (IBD). We reviewed current data and …

STRIDE-II: an update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD …

D Turner, A Ricciuto, A Lewis, F D'amico, J Dhaliwal… - Gastroenterology, 2021 - Elsevier
Background The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)
initiative of the International Organization for the Study of Inflammatory Bowel Diseases …

Therapeutic drug monitoring of biologics in inflammatory bowel disease: unmet needs and future perspectives

K Papamichael, W Afif, D Drobne… - The lancet …, 2022 - thelancet.com
Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimising the use of
biologics, and in particular anti-tumour necrosis factor (anti-TNF) therapy, in inflammatory …

Maintenance adalimumab concentrations are associated with biochemical, endoscopic, and histologic remission in inflammatory bowel disease

A Juncadella, K Papamichael, BP Vaughn… - Digestive diseases and …, 2018 - Springer
Background A treat-to-target therapeutic approach is emerging as the new standard of care
for treating inflammatory bowel disease (IBD), Crohn's disease (CD), and ulcerative colitis …

Cost-effectiveness of therapeutic drug monitoring of anti-TNF therapy in inflammatory bowel disease: a systematic review

S Marquez-Megias, R Nalda-Molina, J Sanz-Valero… - Pharmaceutics, 2022 - mdpi.com
Infliximab and adalimumab are monoclonal antibodies against tumor necrosis factor (anti-
TNF) used to manage inflammatory bowel disease (IBD). Therapeutic Drug Monitoring …

Fecal calprotectin pretreatment and induction infliximab levels for prediction of primary nonresponse to infliximab therapy in Crohn's disease

B Beltrán, M Iborra, E Sáez-González… - Digestive …, 2019 - karger.com
Introduction: The association between infliximab (IFX) and fecal calprotectin (FC) levels on
one hand, and the clinical and endoscopic response of patients with inflammatory bowel …

Multi-utility of therapeutic drug monitoring in inflammatory bowel diseases

CA Martins, KS Garcia, NSF Queiroz - Frontiers in Medicine, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) treatment targets have progressed over time from clinical
response to clinical and endoscopic remission. Several data have shown a positive …

Therapeutic drug monitoring of biologics in Crohn's disease

LB Grossberg, AS Cheifetz… - Gastroenterology …, 2022 - gastro.theclinics.com
Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) that is characterized by
transmural inflammation that can affect any part of the gastrointestinal tract, leading to …

Optimizing therapeutic drug monitoring in inflammatory bowel disease: a focus on therapeutic monoclonal antibodies

K Papamichael, AS Cheifetz - Expert Opinion on Drug Metabolism …, 2021 - Taylor & Francis
Introduction Therapeutic drug monitoring (TDM) is useful for optimizing monoclonal
antibodies (mAbs) for the treatment of immune-mediated inflammatory disorders including …